Department of Primary and Community Care, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, the Netherlands.
Radboudumc Alzheimer Center, Nijmegen, the Netherlands.
Aging Ment Health. 2021 Aug;25(8):1442-1451. doi: 10.1080/13607863.2020.1786799. Epub 2020 Jun 30.
We investigated the 2-week prevalence and correlates of very frequent physical aggression (PA) and vocalizations in nursing home (NH)-residents with dementia.
METHOD/DESIGN: This cross-sectional study used combined data of 2074 NH-residents from four studies, collected from 119 dementia special care units in 26 Dutch NH. Very frequent PA was defined as scoring 6 or 7 on the items 'hitting', pushing', 'biting' and 'kicking' of the Cohen Mansfield Agitation Inventory; very frequent vocalizations as scoring 6 or 7 on 'screaming' and 'making strange noises'. We compared NH-residents with very frequent PA or vocalizations with residents with less frequent PA or vocalizations, assessing correlates using univariate and multivariate multilevel logistic regression analyses.
We found a 2-week prevalence of 2.2% (95% confidence interval (CI): 1.63-2.89) of very frequent PA and 11.5% of very frequent vocalizations (95% CI: 10.23-12.98). Very frequent PA was only associated with apathy (odds ratio (OR)=1.93, 95% CI: 1.04-3.61). Correlates of very frequent vocalizations were age (OR = 0.97, 95% CI: 0.951-0.998), dementia severity (overall -value 0.020), antipsychotic drug use (OR = 1.56, 95% CI: 1.08-2.26), antiepileptic drug use (OR = 2.75, 95% CI: 1.34-5.68) and euphoria (OR = 2.01, 95% CI: 1.22-3.31).
Characteristics of NH-residents with very frequent PA or very frequent vocalizations differ from those of NH-residents with less frequent PA or vocalizations. Frontal lobe damage, boredom, pain and/or external factors may explain several of the found associations, but further research is necessary. Our findings may contribute to better care for these residents and thereby to improving their quality of life.
我们调查了养老院(NH)中患有痴呆症的居民在两周内出现非常频繁的身体侵犯(PA)和发声的流行率及其相关因素。
方法/设计:本横断面研究使用了来自四项研究的 2074 名 NH 居民的合并数据,这些数据来自荷兰 26 个 NH 的 119 个痴呆特殊护理单元。非常频繁的 PA 定义为 Cohen-Mansfield 激越量表的“打人”、“推人”、“咬人”和“踢人”项目中得分为 6 或 7;非常频繁的发声定义为“尖叫”和“发出奇怪的声音”项目中得分为 6 或 7。我们将有非常频繁 PA 或发声的 NH 居民与有较少频繁 PA 或发声的居民进行了比较,使用单变量和多变量多层次逻辑回归分析评估了相关因素。
我们发现两周内非常频繁的 PA 的流行率为 2.2%(95%置信区间(CI):1.63-2.89),非常频繁的发声的流行率为 11.5%(95%CI:10.23-12.98)。非常频繁的 PA 仅与淡漠(优势比(OR)=1.93,95%CI:1.04-3.61)相关。非常频繁发声的相关因素为年龄(OR=0.97,95%CI:0.951-0.998)、痴呆严重程度(总 - 值 0.020)、抗精神病药物使用(OR=1.56,95%CI:1.08-2.26)、抗癫痫药物使用(OR=2.75,95%CI:1.34-5.68)和欣快(OR=2.01,95%CI:1.22-3.31)。
有非常频繁 PA 或非常频繁发声的 NH 居民的特征与有较少频繁 PA 或发声的 NH 居民不同。额叶损伤、无聊、疼痛和/或外部因素可能解释了一些发现的关联,但需要进一步研究。我们的研究结果可能有助于更好地照顾这些居民,从而提高他们的生活质量。