Peremans L, Declercq D, Vande Velde S, De Bruyne R, Van Winckel M, Vande Walle J, Van Biervliet S
Department of paediatrics, Ghent University Hospital.
Cystic Fibrosis Centre, Ghent University Hospital.
Acta Gastroenterol Belg. 2020 Apr-Jun;83(2):315-318.
Most episodes of vomiting, reduced intake and diarrhoea in children can be evaluated and treated without additional tests. However, when the degree of clinical dehydration is not in line with the patient's medical history, other diagnoses should be suspected. In the presence of a hyponatraemic hypochloraemic metabolic alkalosis, cystic fibrosis (CF) should be included in the differential diagnosis, especially if there is failure to thrive even in the absence of respiratory symptoms. Furthermore, young patients diagnosed with CF have a higher risk for an acute electrolyte decompensation caused by increased salt and fluid losses. We present 4 paediatric cases to raise the awareness of electrolyte disturbances in CF patients.
大多数儿童呕吐、摄入量减少和腹泻的情况无需额外检查即可进行评估和治疗。然而，当临床脱水程度与患者病史不符时，应怀疑其他诊断。存在低钠低氯性代谢性碱中毒时，鉴别诊断应包括囊性纤维化（CF），尤其是即使没有呼吸道症状但存在生长发育迟缓的情况。此外，被诊断为CF的年轻患者因盐和液体流失增加而发生急性电解质失衡的风险更高。我们介绍4例儿科病例，以提高对CF患者电解质紊乱的认识。
