Department of Surgery and Pathology, Miguel Hernández University, 03550 Alicante, Spain.
Grupo de Investigación en Terapia Ocupacional (InTeO), Miguel Hernández University, 03550 Alicante, Spain.
Int J Environ Res Public Health. 2020 Jun 26;17(12):4593. doi: 10.3390/ijerph17124593.
Telomere length in early life has been recently associated with biological aging and development of negative consequences in later adult life. A relevant area of research has emerged to understand the factors that impact telomere length in children. We conducted a bibliometric analysis to track research output and identify global trends and gaps in the knowledge of telomere length in children. Bibliographic data were retrieved from the Web of Science database and then analyzed by using Bibliometrix R package. A total of 840 publications were yielded from 1991 to 2019. The references were prominently published in journals, with 20 high ranked journals contributing to 30% of literature on telomere length in children. The USA was the most productive country (35.7%), followed by Europe (12.1%), and Asia (11.9%). A knowledge map of telomere length in children through keyword analyses revealed that there were two potential main lines of research based on two different approaches: genomic research and epidemiological research. This study shows that telomere length in children is a topic of research that has gained significant relevance in the last decade. This bibliometric study may be helpful in identifying research trends and finding research hot spots and gaps in this research field.
近年来,端粒长度与生物衰老以及成年后负面后果的发展有关。为了了解影响儿童端粒长度的因素,出现了一个相关的研究领域。我们进行了文献计量分析,以跟踪研究成果,并确定儿童端粒长度知识的全球趋势和差距。文献数据从 Web of Science 数据库中检索,然后使用 Bibliometrix R 包进行分析。从 1991 年到 2019 年,共产生了 840 篇出版物。这些参考文献主要发表在期刊上,有 20 种高排名期刊贡献了儿童端粒长度文献的 30%。美国是最具生产力的国家(35.7%),其次是欧洲(12.1%)和亚洲(11.9%)。通过关键词分析绘制的儿童端粒长度知识图谱表明,有两条潜在的主要研究线,基于两种不同的方法:基因组研究和流行病学研究。本研究表明,儿童端粒长度是过去十年中一个具有重要意义的研究课题。这项文献计量研究可能有助于确定该研究领域的研究趋势和发现研究热点和差距。