四种源自传统中药材的植物提取物对肠炎沙门氏菌肠炎亚种的抗菌活性
Antibacterial Activity of Four Plant Extracts Extracted from Traditional Chinese Medicinal Plants against and subsp. serovar Enteritidis.
作者信息
McMurray R L, Ball M E E, Tunney M M, Corcionivoschi N, Situ C
机构信息
Queen's University Belfast, School of Biological Sciences, Belfast BT9 5DL, Northern Ireland, UK.
Agri-Food and Biosciences Institute, Hillsborough BT26 6DR, Northern Ireland, UK.
出版信息
Microorganisms. 2020 Jun 26;8(6):962. doi: 10.3390/microorganisms8060962.
The worldwide ethnobotanical use of four investigated plants indicates antibacterial properties. The aim of this study was to screen and determine significant antibacterial activity of four plant extracts in vitro and in a poultry digest model. Using broth microdilution, the concentrations at which four plant extracts inhibited and over 24 hours was determined. Ledeb (L.) Goldblatt and Mabb Bunge and Roxb all exhibited a minimum inhibitory concentration (MIC) of 62.5mg/L and a minimum bactericidal concentration (MBC) of 500mg/L against one pathogen. Ledeb was the most effective against and with the exception of , for which Bunge was the most effective. Time-kills of Ledeb and Bunge against and incubated in poultry cecum were used to determine bactericidal activity of these plant extracts. Bunge significantly reduced by ≥ 99.99% within 6 hours. exhibited effective significant bactericidal activity within 4 hours against and . This paper highlights the potential of these plant extracts to control pathogens commonly found in the poultry gastrointestinal tract.
对四种被研究植物的全球民族植物学用途研究表明它们具有抗菌特性。本研究的目的是筛选并确定四种植物提取物在体外和家禽消化模型中的显著抗菌活性。采用肉汤微量稀释法，测定了四种植物提取物在24小时内抑制（细菌生长）的浓度。Ledeb (L.) Goldblatt和Mabb、Bunge以及Roxb对一种病原体均表现出最低抑菌浓度（MIC）为62.5mg/L，最低杀菌浓度（MBC）为500mg/L。Ledeb对（某种细菌）最有效，除了（另一种细菌），对于（这种细菌）Bunge最有效。利用在禽类盲肠中培养的Ledeb和Bunge对（相关细菌）的时间-杀菌曲线来确定这些植物提取物的杀菌活性。Bunge在6小时内将（细菌数量）显著降低了≥99.99%。（某种植物提取物）在4小时内对（相关细菌）表现出有效的显著杀菌活性。本文强调了这些植物提取物在控制家禽胃肠道中常见病原体方面的潜力。
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