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电子烟或雾化产品使用相关肺损伤(EVALI)病例回顾及文献简要综述

Review of Cases of E-Cigarette or Vaping Product Use-Associated Lung Injury (EVALI) and Brief Review of the Literature.

作者信息

Essa Amr, Macaraeg Jeffrey, Jagan Nikhil, Kwon Daniel, Randhawa Saboor, Kruse Matthew, Thomas Stanley, Velagapudi Manasa, Horne John, Narechania Shraddha, Kaster Michael, Valenta Carrie, Sahasranaman Venketraman, Moore Douglas

机构信息

Creighton University School of Medicine, Department of Internal Medicine, Omaha, USA.

Creighton University School of Medicine, Department of Pulmonary, Critical Care, and Sleep Medicine, Omaha, USA.

出版信息

Case Rep Pulmonol. 2020 Jun 14;2020:1090629. doi: 10.1155/2020/1090629. eCollection 2020.

Abstract

Since the appearance of the E-Cigarette in the early 2000s, its industry, popularity, and prevalence have risen dramatically. In the past, E-Cigarette use with the vaping of nicotine or cannabis products had been associated with a few reported cases of lung injury. However, in 2019, thousands of cases of E-Cigarette or vaping product use-associated lung injury (EVALI) were reported in the United States. Evidence linked this outbreak with vaping of tetrahydrocannabinol (THC). We report two confirmed cases of EVALI and their associated clinical, radiologic, and pathologic features. This report supports the growing body of information regarding EVALI. It also discusses various substances, particularly vitamin E acetate, which has been suggested as a causative agent.

摘要

自21世纪初电子烟出现以来,其行业规模、受欢迎程度和普及率都急剧上升。过去,使用电子烟吸食尼古丁或大麻产品曾与少数几例报告的肺损伤病例有关。然而,2019年,美国报告了数千例与使用电子烟或雾化产品相关的肺损伤(EVALI)病例。有证据表明,此次疫情爆发与四氢大麻酚(THC)雾化有关。我们报告了两例确诊的EVALI病例及其相关的临床、放射学和病理学特征。本报告支持了关于EVALI的越来越多的信息。它还讨论了各种物质,特别是维生素E醋酸酯,有人认为它是一种致病因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ed8/7313101/44294a60247d/CRIPU2020-1090629.001.jpg

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