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肿胀性红斑狼疮:一种罕见且独特的皮肤红斑狼疮变体,伪装成荨麻疹性血管炎。

Tumid Lupus Erythematosus: A Rare and Distinctive Variant of Cutaneous Lupus Erythematosus Masquerading as Urticarial Vasculitis.

作者信息

Liu Evan, Daze Robert P, Moon Summer

机构信息

Dermatology, Nova Southeastern University, Dr. Kiran C. Patel College of Osteopathic Medicine, Largo, USA.

Dermatology, Largo Medical Center, Largo, USA.

出版信息

Cureus. 2020 May 26;12(5):e8305. doi: 10.7759/cureus.8305.

Abstract

Tumid lupus erythematosus (TLE) is a rare form of chronic cutaneous lupus that has triggered much debate regarding its clinical and histopathological features. It has been classically defined as annular erythematous, succulent, plaques involving the face and trunk that typically are devoid of any papulosquamous features such as scale and follicular plugging. These lesions are a clinical mimicker of other urticarial lesions such as urticarial vasculitis and lymphocytic infiltrate of Jessner. We report a case of TLE presenting in a 49-year-old Caucasian female whose initial clinical presentation was concerning for urticarial vasculitis due to presence of urticarial-like lesions present for approximately three months. Laboratory studies and histopathological correlations confirmed the diagnosis of TLE and the patient was successfully treated with topical corticosteroids.

摘要

肿胀性红斑狼疮(TLE)是一种罕见的慢性皮肤型狼疮,其临床和组织病理学特征引发了诸多争论。它传统上被定义为累及面部和躯干的环形红斑、多汁性斑块,通常没有任何丘疹鳞屑性特征,如鳞屑和毛囊堵塞。这些损害在临床上可模仿其他荨麻疹性损害,如荨麻疹性血管炎和杰斯纳淋巴细胞浸润症。我们报告一例49岁白种女性的TLE病例,其最初临床表现因存在类似荨麻疹的损害约三个月而疑似荨麻疹性血管炎。实验室检查和组织病理学关联证实了TLE的诊断,患者经外用糖皮质激素治疗成功。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf8e/7320659/671a0ffd5689/cureus-0012-00000008305-i01.jpg

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