Madina Syeda Rabi, Bacha Raham, Gilani Syed Amir, Fatima Wafa, Awais Wahida, Fatima Hamnah, Manzoor Iqra
University Institute of Radiological Sciences and Medical Imaging Technologies (UIRSMIT), Faculty of Allied Health Sciences (FAHS), University of Lahore , Lahaur , Pakistan.
University Institute of Public Health (UIPH), Faculty of Allied Health Sciences (FAHS), University of Lahore , Lahaur , Pakistan.
J Ultrason. 2020;20(81):e95-e99. doi: 10.15557/JoU.2020.0015. Epub 2020 Jun 15.
Preeclampsia is a medical condition characterized by hypertension and proteinuria during pregnancy, with the symptoms generally manifesting in the 3 trimester. Hypertension brings hemodynamic changes; it is therefore expected that arterial blood flow velocity waveforms will be different in the uterine and ophthalmic arteries in preeclampsia. Vascular changes do occur in preeclampsia, which in turn induces hemodynamic changes. To compare mean values of the resistive index of the ophthalmic and uterine arteries in patients with preeclampsia and normotensive individuals in Doppler US. In this cross-sectional observational study, ultrasound of the uterine and ophthalmic arteries was performed in 60 pregnant women in the 2 and 3 trimester of pregnancy to compare the resistive index of these arteries in preeclamptic and normotensive individuals. All the patients, i.e. 30 preeclamptic and 30 normotensive pregnant women, took part in this study voluntarily. The study was approved by the institutional review board (IRB) of the University of Lahore. The mean resistive index of the uterine artery was 0.50 ± 0.08 in normotensive participants and 0.64 ± 0.09 in preeclamptic women, with the -value <0.001. The mean resistive index of the ophthalmic artery was 0.70 ± 0.05 in normotensive participants and 0.63 ± 0.04 in preeclamptic women, with the -value <0.001. There was a significant negative correlation between the resistive index of the uterine and ophthalmic arteries among the patients with preeclampsia and a significant positive correlation among normotensive individuals. Preeclampsia could be easily diagnosed with Doppler ultrasound based on hemodynamic changes in response to vascular changes in the ophthalmic and uterine arteries. Preeclampsia is a medical condition characterized by hypertension and proteinuria during pregnancy, with the symptoms generally manifesting in the 3 trimester. Hypertension brings hemodynamic changes; it is therefore expected that arterial blood flow velocity waveforms will be different in the uterine and ophthalmic arteries in preeclampsia. Vascular changes do occur in preeclampsia, which in turn induces hemodynamic changes. To compare mean values of the resistive index of the ophthalmic and uterine arteries in patients with preeclampsia and normotensive individuals in Doppler US. In this cross-sectional observational study, ultrasound of the uterine and ophthalmic arteries was performed in 60 pregnant women in the 2 and 3 trimester of pregnancy to compare the resistive index of these arteries in preeclamptic and normotensive individuals. All the patients, i.e. 30 preeclamptic and 30 normotensive pregnant women, took part in this study voluntarily. The study was approved by the institutional review board (IRB) of the University of Lahore. The mean resistive index of the uterine artery was 0.50 ± 0.08 in normotensive participants and 0.64 ± 0.09 in preeclamptic women, with the -value <0.001. The mean resistive index of the ophthalmic artery was 0.70 ± 0.05 in normotensive participants and 0.63 ± 0.04 in preeclamptic women, with the -value <0.001. There was a significant negative correlation between the resistive index of the uterine and ophthalmic arteries among the patients with preeclampsia and a significant positive correlation among normotensive individuals. Preeclampsia could be easily diagnosed with Doppler ultrasound based on hemodynamic changes in response to vascular changes in the ophthalmic and uterine arteries.
子痫前期是一种孕期以高血压和蛋白尿为特征的病症，症状通常在孕晚期出现。高血压会带来血流动力学变化；因此预计子痫前期患者子宫动脉和眼动脉的血流速度波形会有所不同。子痫前期确实会发生血管变化，进而引发血流动力学变化。在多普勒超声检查中比较子痫前期患者与血压正常个体眼动脉和子宫动脉阻力指数的平均值。在这项横断面观察性研究中，对60名处于妊娠中晚期的孕妇进行了子宫动脉和眼动脉超声检查，以比较子痫前期患者和血压正常个体这些动脉的阻力指数。所有患者，即30名单纯收缩期高血压孕妇和30名血压正常的孕妇，均自愿参与本研究。该研究经拉合尔大学机构审查委员会（IRB）批准。血压正常参与者子宫动脉的平均阻力指数为0.50±0.08，子痫前期女性为0.64±0.09，P值<0.001。血压正常参与者眼动脉的平均阻力指数为0.70±0.05，子痫前期女性为0.63±0.04，P值<0.001。子痫前期患者子宫动脉和眼动脉的阻力指数之间存在显著负相关，而血压正常个体之间存在显著正相关。基于眼动脉和子宫动脉血管变化引起的血流动力学变化，子痫前期可通过多普勒超声轻松诊断。子痫前期是一种孕期以高血压和蛋白尿为特征的病症，症状通常在孕晚期出现。高血压会带来血流动力学变化；因此预计子痫前期患者子宫动脉和眼动脉的血流速度波形会有所不同。子痫前期确实会发生血管变化，进而引发血流动力学变化。在多普勒超声检查中比较子痫前期患者与血压正常个体眼动脉和子宫动脉阻力指数的平均值。在这项横断面观察性研究中，对60名处于妊娠中晚期的孕妇进行了子宫动脉和眼动脉超声检查，以比较子痫前期患者和血压正常个体这些动脉的阻力指数。所有患者，即30名单纯收缩期高血压孕妇和30名血压正常的孕妇，均自愿参与本研究。该研究经拉合尔大学机构审查委员会（IRB）批准。血压正常参与者子宫动脉的平均阻力指数为0.50±0.08，子痫前期女性为0.64±0.09，P值<0.001。血压正常参与者眼动脉的平均阻力指数为0.70±0.05，子痫前期女性为0.63±0.04，P值<0.001。子痫前期患者子宫动脉和眼动脉的阻力指数之间存在显著负相关，而血压正常个体之间存在显著正相关。基于眼动脉和子宫动脉血管变化引起的血流动力学变化，子痫前期可通过多普勒超声轻松诊断。
