Department of Surgical, Medical, Molecular and Critical Area Pathology, Unit of Pediatric Dentistry, University of Pisa, Pisa, Italy.
Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, Dental Clinic, University of Pisa, Pisa, Italy.
J Biol Regul Homeost Agents. 2020 May-Jun;34(3 Suppl. 1):129-137. DENTAL SUPPLEMENT.
Sjögren's Syndrome is a complex disease, due to an autoimmune physiopathology, that strongly impacts both patients' primary needs (nutrition and speaking), and patients' relationship life related factors (psychological health and quality of life). In Literature, few studies had investigated oral health status in Sjögren's syndrome and its impact on patients' quality of life, so the aim of this study was to analyse that issue. 30 patients were enrolled, within the Department of Rheumatology (University of Pisa), both first diagnosis patients' and both patients who had been diagnosed with Sjögren's syndrome in the past. For each patient, a medical record was filled out together with the compilation of the Oral Health Impact Profile questionnaire. Then, during a specialistic rheumatologic visit, Sjögren's Syndrome Disease Damage Index Score (SSDDI) was determined. Results showed a direct proportion between years from diagnosis and severity of oral health issues. It was found that these issues were related to soft tissue damage and an overall worse, reported quality of life and psychological health.
干燥综合征是一种复杂的疾病，由于自身免疫的病理生理学，它严重影响了患者的主要需求（营养和说话），以及患者的生活相关因素（心理健康和生活质量）。在文献中，很少有研究调查干燥综合征的口腔健康状况及其对患者生活质量的影响，因此本研究旨在分析这个问题。30 名患者被纳入风湿病科（比萨大学），包括首次诊断的患者和过去已被诊断为干燥综合征的患者。对于每个患者，填写一份病历，并同时编制口腔健康影响调查问卷。然后，在专门的风湿科就诊时，确定干燥综合征疾病损伤指数评分（SSDDI）。结果表明，从诊断到口腔健康问题严重程度之间存在直接比例关系。结果发现，这些问题与软组织损伤有关，整体上报告的生活质量和心理健康状况更差。
