Snider Sam, Costello Collin M, Ederaine Sophia, Besch-Stokes Jake, Severson Kevin J, DiCaudo David J, Pittelkow Mark R, Mangold Aaron R
Mayo Clinic Alix School of Medicine, Scottsdale, AZ, USA.
Department of Dermatology, Mayo Clinic, Scottsdale, AZ, USA.
Pediatr Dermatol. 2020 Sep;37(5):881-883. doi: 10.1111/pde.14244. Epub 2020 Jul 3.
We report a case of a 13-year-old boy with extensive lymphomatoid papulosis (LyP) involving his elbows, forearms, proximal thighs, and right hip, with treatment-resistant nodules on his right forearm. He was treated with full-body narrowband ultraviolet B and targeted photodynamic therapy (PDT) with 20% aminolevulinic acid (ALA). After two months, there was complete resolution of the right forearm nodules. Due to its minimal toxicity, PDT offers unique advantages and may be considered for pediatric LyP patients with symptomatic, localized disease resistant to conventional treatments.
我们报告一例13岁男孩，患有广泛的淋巴瘤样丘疹病（LyP），累及肘部、前臂、大腿近端和右髋部，右前臂有治疗抵抗性结节。他接受了全身窄谱紫外线B照射以及用20%氨基乙酰丙酸（ALA）进行的靶向光动力疗法（PDT）。两个月后，右前臂结节完全消退。由于其毒性极小，PDT具有独特优势，对于有症状的、局部病变且对传统治疗耐药的儿童LyP患者可考虑使用。
