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儿童和青少年的睡眠时间与心血管危险因素:系统评价。

Sleep duration and cardiovascular risk factors in children and adolescents: A systematic review.

机构信息

Department of Epidemiology, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China; The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Department of Cardiology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China; Department of Child Health, School of Public Health, Huazhong University of Science and Technology, Wuhan, China.

Department of Epidemiology, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.

出版信息

Sleep Med Rev. 2020 Oct;53:101338. doi: 10.1016/j.smrv.2020.101338. Epub 2020 May 19.

Abstract

An association between short sleep duration and cardiovascular risk factors and outcomes is well demonstrated in adults. However, findings on the association in children and adolescents have been inconsistent. In this review, we searched PubMed, Embase and ISI Web of Science for eligible publications until March 16, 2020. We identified 37 reviews/meta-analyses on the association between sleep duration and cardiovascular risk factors and 15 studies on the association between sleep duration and metabolic syndrome (MetS) in children and adolescents. We found strong evidence on the association between short sleep duration and increased adiposity markers and high blood pressure, some evidence on the association between short sleep duration and insulin resistance, but inconsistent findings on the association between sleep duration and blood lipids, inflammation and MetS. Although more studies are needed to further assess the association between sleep duration and selected cardiovascular risk factors, our findings support interventions to improve sleep duration and quality as a potential means to promote cardiovascular health in children and adolescents.

摘要

已有大量研究证明,睡眠时长与心血管风险因素和结局之间存在关联,这种关联在成年人中表现得尤为明显。然而,关于儿童和青少年的相关研究结果却并不一致。本综述检索了PubMed、Embase 和 ISI Web of Science 中截至 2020 年 3 月 16 日的相关文献,共纳入 37 篇关于睡眠时长与心血管风险因素关联的综述/荟萃分析,以及 15 篇关于睡眠时长与儿童和青少年代谢综合征(MetS)关联的研究。研究结果表明,较短的睡眠时长与肥胖标志物增加和高血压之间存在密切关联,且有一定证据表明较短的睡眠时长与胰岛素抵抗之间存在关联,但关于睡眠时长与血脂、炎症和 MetS 之间的关联,目前还存在不一致的研究结果。尽管还需要更多的研究来进一步评估睡眠时长与某些心血管风险因素之间的关联,但我们的研究结果支持通过改善睡眠时长和质量来促进儿童和青少年心血管健康的干预措施。

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