Department of Ophthalmology, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310027, China.
State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, China.
Sci China Life Sci. 2020 Oct;63(10):1450-1490. doi: 10.1007/s11427-019-1684-x. Epub 2020 Jul 2.
Regenerative medicine (RM) is one of the most promising disciplines for advancements in modern medicine, and regenerative ophthalmology (RO) is one of the most active fields of regenerative medicine. This review aims to provide an overview of regenerative ophthalmology, including the range of tools and materials being used, and to describe its application in ophthalmologic subspecialties, with the exception of surgical implantation of artificial tissues or organs (e.g., contact lens, artificial cornea, intraocular lens, artificial retina, and bionic eyes) due to space limitations. In addition, current challenges and limitations of regenerative ophthalmology are discussed and future directions are highlighted.
再生医学(RM)是现代医学进步最有前途的学科之一,而再生眼科学(RO)是再生医学最活跃的领域之一。本综述旨在概述再生眼科学,包括正在使用的工具和材料的范围,并描述其在眼科亚专业中的应用,但由于篇幅限制,不包括人工组织或器官的手术植入(例如隐形眼镜、人工角膜、人工晶状体、人工视网膜和仿生眼)。此外,还讨论了再生眼科学目前面临的挑战和局限性,并强调了未来的发展方向。