Pope H G, McElroy S L, Nixon R A
Epidemiology Laboratory, McLean Hospital, Belmont, MA 02178.
Am J Psychiatry. 1988 Oct;145(10):1292-4. doi: 10.1176/ajp.145.10.1292.
Five depressed patients who had shown no improvement with trials of antidepressants from several chemical families, including fluoxetine, responded when lithium was given in conjunction with fluoxetine. Lithium augmentation of fluoxetine may represent a useful strategy in refractory depression.
五名抑郁症患者在使用包括氟西汀在内的几种化学类抗抑郁药进行试验时均未见改善，但在将锂盐与氟西汀联合使用后有了反应。锂盐增强氟西汀的作用可能是难治性抑郁症的一种有用策略。
