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生姜对牙周手术后疼痛的疗效——一项随机交叉临床试验。

Effectiveness of ginger on pain following periodontal surgery - A randomized cross-over clinical trial.

作者信息

Menon Pallavi, Perayil Jayachandran, Fenol Angel, Rajan Peter Maya, Lakshmi P, Suresh Reshma

机构信息

Department of Periodontics, Amrita School of Dentistry, Kochi, Amrita Vishwa Vidyapeetham, India.

Department of Periodontics, Amrita School of Dentistry, Kochi, Amrita Vishwa Vidyapeetham, India.

出版信息

J Ayurveda Integr Med. 2021 Jan-Mar;12(1):65-69. doi: 10.1016/j.jaim.2020.05.003. Epub 2020 Jul 2.

Abstract

BACKGROUND

Ibuprofen is one of the generally prescribed Non-steroidal anti-inflammatory drugs (NSAIDs) for postoperative pain after periodontal surgery, but are contraindicated in certain patients. Ginger, which is the rhizome of Zingiber officinale, being a common herbal drug having anti-inflammatory as well as analgesic activities can be an efficient substitute for synthetic agents like Ibuprofen.

OBJECTIVES

To compare the effectiveness of ibuprofen and dried ginger powder on pain and gingival inflammation following open flap debridement.

MATERIALS AND METHODS

Ten systemically healthy individuals with chronic generalized periodontitis were selected for this single-blinded randomized cross-over clinical trial and underwent open flap debridement in at least two quadrants. Each quadrant was randomly allocated to receive either Ibuprofen (400 mg) or Ginger powder capsules (400 mg) thrice daily for three days. Subjects were requested to note down the pain score on the Visual Analogue Scale (VAS) provided in a printed format, for the first eight hours after surgery and on the following two days, and gingival inflammation was assessed after one week, using Modified Gingival Index (MGI).

RESULT

The difference in the VAS score and MGI between the two groups was not of statistical significance.

CONCLUSION

Effectiveness of ginger powder for the management of pain and gingival inflammation following open flap debridement is comparable to that of ibuprofen.

摘要

背景

布洛芬是牙周手术后术后疼痛常用的非甾体抗炎药之一,但在某些患者中禁用。生姜是姜科植物姜的根茎,作为一种常见的具有抗炎和镇痛活性的草药,可有效替代布洛芬等合成药物。

目的

比较布洛芬和干姜粉对开放瓣清创术后疼痛和牙龈炎症的疗效。

材料与方法

选取10名患有慢性广泛性牙周炎的全身健康个体进行这项单盲随机交叉临床试验,至少在两个象限进行开放瓣清创术。每个象限随机分配,每天三次服用布洛芬(400毫克)或干姜粉胶囊(400毫克),持续三天。要求受试者在术后头八小时及接下来的两天,按照提供的印刷格式记录视觉模拟量表(VAS)上的疼痛评分,并在一周后使用改良牙龈指数(MGI)评估牙龈炎症。

结果

两组之间的VAS评分和MGI差异无统计学意义。

结论

干姜粉对开放瓣清创术后疼痛和牙龈炎症管理的疗效与布洛芬相当。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b24a/8039361/47472d923edc/gr1.jpg

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