Sakthivel Varadharaj, Krishnasamy Vembu, Mehalingam Vadivelan
College of Nursing, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Department of Community Health Nursing, College of Nursing, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
J Caring Sci. 2020 Jun 1;9(2):93-97. doi: 10.34172/JCS.2020.014. eCollection 2020 Jun.
Anti-retro viral drugs are the corner stone of management of human immunodeficiency virus (HIV) infection. Anti-retro viral drugs have been consistently proven to reduce mortality due to HIV. The aim of this study was to identify the level of drug adherence and related challenges for adherence. A cross- sectional study was conducted in the antiretroviral therapy (ART) clinic of a tertiary care teaching hospital. Patients who were above 18 years of age, on ART for at least six months and underwent counselling before starting ART were included in the study (n = 143). Demographic variables and clinical profile were noted and level of drug adherence and associated factors were assessed using Morisky Green Levine test and check list respectively. Data was analysed in SPSS version 22. Most of the study subjects (89.5%) had high level of medication adherence and 10.5% had medium level adherence. Factors contributing to high adherence level were confidentiality and trust among health workers, concerned about their own health, understanding about the prescribed drugs, idea about disease progression, effectiveness and knowledge of anti-retro viral drugs. Drug adherence was found to be high among HIV- infected patients in this study and various reasons contributed for the high adherence among the study subjects.
抗逆转录病毒药物是治疗人类免疫缺陷病毒（HIV）感染的基石。抗逆转录病毒药物已被反复证明可降低HIV导致的死亡率。本研究的目的是确定药物依从性水平以及依从性相关挑战。在一家三级护理教学医院的抗逆转录病毒治疗（ART）诊所开展了一项横断面研究。纳入研究的患者年龄在18岁以上，接受ART治疗至少6个月且在开始ART治疗前接受过咨询（n = 143）。记录人口统计学变量和临床特征，并分别使用Morisky Green Levine测试和检查表评估药物依从性水平及相关因素。数据在SPSS 22版中进行分析。大多数研究对象（89.5%）药物依从性水平高，10.5%为中等依从性水平。促成高依从性水平的因素包括医护人员之间的保密性和信任、对自身健康的关注、对所开药物的理解、对疾病进展的认识、抗逆转录病毒药物的有效性和知识。本研究发现HIV感染患者的药物依从性较高，且多种原因促成了研究对象的高依从性。
