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埃塞俄比亚迪拉大学转诊医院产前诊所孕妇淋病和梅毒感染的决定因素:非匹配病例对照研究。

Determinants of gonorrhea and syphilis infections among pregnant women attending antenatal clinic at Dilla University Referral Hospital, Ethiopia: Unmatched case-control study.

作者信息

Hailu Kumneger, Gebretsadik Achamyelesh

机构信息

Gedio Zone Health Office, Dilla, Ethiopia.

School of Public Health, Hawassa University, Hawassa, Ethiopia.

出版信息

Womens Health (Lond). 2020 Jan-Dec;16:1745506520940095. doi: 10.1177/1745506520940095.

Abstract

OBJECTIVE

This study was designed to determine the risk factors associated with gonorrhea and syphilis infections among pregnant women attending antenatal care clinic at Dilla University Referral Hospital.

METHOD

A hospital-based unmatched case-control study (64 cases and 128 controls) with 1:2 ratios was conducted from 29 January 2018 to 20 June 2018, at the antenatal care clinic of the Dilla University Referral Hospital. Venous blood and vaginal swab were collected to screen for gonorrhea and syphilis. A pretested interviewer-administered questionnaire was used to gather data on sociodemographic and predisposing factors. Logistic regression analysis used to identify risk factors for sexually transmitted infections among pregnant women at 95% confidence interval and -value < 0.05.

RESULT

A total of 64 cases of syphilis or gonorrhea were identified with a mean age of 26 years (±4.1 years.). Of those cases, 40 were syphilis seropositive and the remaining were gonorrhea cases. Lower educational status (adjusted odds ratio = 2.4, 95% confidence interval: 1.1-4.9), age of first sex <18 years (adjusted odds ratio = 2.8, 95% confidence interval: 1.3-5.9), history of abortion (adjusted odds ratio = 3.1, 95% confidence interval: 1.4-6.6), and having two or more sexual partners in the past year (adjusted odds ratio = 2.5, 95% confidence interval: 1.1-5.7) were significantly associated with gonorrhea and syphilis infection.

CONCLUSION

Demographic, behavioral, and obstetric factors are associated with the occurrence of syphilis or gonorrhea among pregnant women. Strengthening the existing antenatal care services, providing health education on risk factors, and prioritizing women with the risk characteristics and initiation of gonorrhea and syphilis screening during antennal care are mandatory.

摘要

目的

本研究旨在确定迪拉大学转诊医院产前保健诊所就诊的孕妇中与淋病和梅毒感染相关的危险因素。

方法

2018年1月29日至2018年6月20日,在迪拉大学转诊医院的产前保健诊所进行了一项基于医院的非匹配病例对照研究(64例病例和128例对照),比例为1:2。采集静脉血和阴道拭子以筛查淋病和梅毒。使用预先测试的访谈员管理问卷收集社会人口统计学和诱发因素的数据。采用逻辑回归分析确定95%置信区间且P值<0.05的孕妇性传播感染危险因素。

结果

共确定64例梅毒或淋病病例,平均年龄26岁(±4.1岁)。其中,40例梅毒血清学阳性,其余为淋病病例。较低的教育水平(调整比值比=2.4,95%置信区间:1.1-4.9)、首次性行为年龄<18岁(调整比值比=2.8,95%置信区间:1.3-5.9)、流产史(调整比值比=3.1,95%置信区间:1.4-6.6)以及过去一年有两个或更多性伴侣(调整比值比=2.5,95%置信区间:1.1-5.7)与淋病和梅毒感染显著相关。

结论

人口统计学、行为和产科因素与孕妇梅毒或淋病的发生有关。加强现有的产前保健服务,提供危险因素健康教育,并对具有风险特征的女性进行优先排序,在产前保健期间开展淋病和梅毒筛查是必不可少的。

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Risk factors for syphilis in women: case-control study.女性梅毒的危险因素:病例对照研究。
Rev Saude Publica. 2017 Aug 17;51:78. doi: 10.11606/S1518-8787.2017051007066.
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Syphilis among pregnant women in Juba, Southern Sudan.苏丹南部朱巴孕妇中的梅毒情况。
East Afr Med J. 2010 May;87(5):192-8. doi: 10.4314/eamj.v87i5.63073.

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