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Risk factors for syphilis in women: case-control study.女性梅毒的危险因素:病例对照研究。
Rev Saude Publica. 2017 Aug 17;51:78. doi: 10.11606/S1518-8787.2017051007066.
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Prevalence and impact of sexually transmitted infections in pregnant women in central Ethiopia.埃塞俄比亚中部孕妇性传播感染的患病率及影响
Int J STD AIDS. 2018 Mar;29(3):251-258. doi: 10.1177/0956462417723545. Epub 2017 Aug 4.
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High prevalence of curable sexually transmitted infections among pregnant women in a rural county hospital in Kilifi, Kenya.肯尼亚基利菲县一家农村县医院的孕妇中可治愈性传播感染的高流行率。
PLoS One. 2017 Mar 31;12(3):e0175166. doi: 10.1371/journal.pone.0175166. eCollection 2017.
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Prevalence of Curable Sexually Transmitted Infections in Pregnant Women in Low- and Middle-Income Countries From 2010 to 2015: A Systematic Review.2010年至2015年低收入和中等收入国家孕妇可治愈性传播感染的患病率:一项系统评价。
Sex Transm Dis. 2016 Jul;43(7):450-8. doi: 10.1097/OLQ.0000000000000460.
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Chlamydia trachomatis Infection in Pregnancy: The Global Challenge of Preventing Adverse Pregnancy and Infant Outcomes in Sub-Saharan Africa and Asia.沙眼衣原体感染与妊娠:在撒哈拉以南非洲和亚洲,预防不良妊娠和婴儿结局的全球性挑战。
Biomed Res Int. 2016;2016:9315757. doi: 10.1155/2016/9315757. Epub 2016 Apr 6.
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Magnitude of HIV and syphilis seroprevalence among pregnant women in Gondar, Northwest Ethiopia: a cross-sectional study.埃塞俄比亚西北部贡德尔地区孕妇中艾滋病毒和梅毒血清阳性率的规模:一项横断面研究。
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Seroprevalence of syphilis and human immunodeficiency virus infections among pregnant women who attend the University of Gondar teaching hospital, Northwest Ethiopia: a cross sectional study.埃塞俄比亚西北部贡德尔大学教学医院就诊孕妇梅毒和人类免疫缺陷病毒感染的血清流行率:一项横断面研究。
BMC Infect Dis. 2015 Mar 3;15:111. doi: 10.1186/s12879-015-0848-5.
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埃塞俄比亚迪拉大学转诊医院产前诊所孕妇淋病和梅毒感染的决定因素:非匹配病例对照研究。

Determinants of gonorrhea and syphilis infections among pregnant women attending antenatal clinic at Dilla University Referral Hospital, Ethiopia: Unmatched case-control study.

作者信息

Hailu Kumneger, Gebretsadik Achamyelesh

机构信息

Gedio Zone Health Office, Dilla, Ethiopia.

School of Public Health, Hawassa University, Hawassa, Ethiopia.

出版信息

Womens Health (Lond). 2020 Jan-Dec;16:1745506520940095. doi: 10.1177/1745506520940095.

DOI:10.1177/1745506520940095
PMID:32628574
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7338641/
Abstract

OBJECTIVE

This study was designed to determine the risk factors associated with gonorrhea and syphilis infections among pregnant women attending antenatal care clinic at Dilla University Referral Hospital.

METHOD

A hospital-based unmatched case-control study (64 cases and 128 controls) with 1:2 ratios was conducted from 29 January 2018 to 20 June 2018, at the antenatal care clinic of the Dilla University Referral Hospital. Venous blood and vaginal swab were collected to screen for gonorrhea and syphilis. A pretested interviewer-administered questionnaire was used to gather data on sociodemographic and predisposing factors. Logistic regression analysis used to identify risk factors for sexually transmitted infections among pregnant women at 95% confidence interval and -value < 0.05.

RESULT

A total of 64 cases of syphilis or gonorrhea were identified with a mean age of 26 years (±4.1 years.). Of those cases, 40 were syphilis seropositive and the remaining were gonorrhea cases. Lower educational status (adjusted odds ratio = 2.4, 95% confidence interval: 1.1-4.9), age of first sex <18 years (adjusted odds ratio = 2.8, 95% confidence interval: 1.3-5.9), history of abortion (adjusted odds ratio = 3.1, 95% confidence interval: 1.4-6.6), and having two or more sexual partners in the past year (adjusted odds ratio = 2.5, 95% confidence interval: 1.1-5.7) were significantly associated with gonorrhea and syphilis infection.

CONCLUSION

Demographic, behavioral, and obstetric factors are associated with the occurrence of syphilis or gonorrhea among pregnant women. Strengthening the existing antenatal care services, providing health education on risk factors, and prioritizing women with the risk characteristics and initiation of gonorrhea and syphilis screening during antennal care are mandatory.

摘要

目的

本研究旨在确定迪拉大学转诊医院产前保健诊所就诊的孕妇中与淋病和梅毒感染相关的危险因素。

方法

2018年1月29日至2018年6月20日,在迪拉大学转诊医院的产前保健诊所进行了一项基于医院的非匹配病例对照研究(64例病例和128例对照),比例为1:2。采集静脉血和阴道拭子以筛查淋病和梅毒。使用预先测试的访谈员管理问卷收集社会人口统计学和诱发因素的数据。采用逻辑回归分析确定95%置信区间且P值<0.05的孕妇性传播感染危险因素。

结果

共确定64例梅毒或淋病病例,平均年龄26岁(±4.1岁)。其中,40例梅毒血清学阳性,其余为淋病病例。较低的教育水平(调整比值比=2.4,95%置信区间:1.1-4.9)、首次性行为年龄<18岁(调整比值比=2.8,95%置信区间:1.3-5.9)、流产史(调整比值比=3.1,95%置信区间:1.4-6.6)以及过去一年有两个或更多性伴侣(调整比值比=2.5,95%置信区间:1.1-5.7)与淋病和梅毒感染显著相关。

结论

人口统计学、行为和产科因素与孕妇梅毒或淋病的发生有关。加强现有的产前保健服务,提供危险因素健康教育,并对具有风险特征的女性进行优先排序,在产前保健期间开展淋病和梅毒筛查是必不可少的。