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老年韩国家庭中配偶身体虚弱的一致性。

Spousal Concordance of Physical Frailty in Older Korean Couples.

机构信息

Department of Medicine, College of Medicine, Kyung Hee University, Seoul 02447, Korea.

Department of Biomedical Science and Technology, College of Medicine, East-West Medical Research Institute, Kyung Hee University, Seoul 02447, Korea.

出版信息

Int J Environ Res Public Health. 2020 Jun 25;17(12):4574. doi: 10.3390/ijerph17124574.

Abstract

Marital status is an important risk factor for physical frailty. However, there are limited data on spousal concordance of physical frailty among married couples. Here, we evaluate the spousal concordance of frailty as defined by the Fried frailty phenotype and specific phenotype components that contribute to this association. Data on 315 married couples (630 individuals) aged between 70 and 84 years were obtained from the Korean Frailty and Aging Cohort Study (KFACS). Multivariate logistic regressions were used for the analysis. After adjusting for covariates (age, body mass index, education, house ownership, comorbidity, cognition, depressive symptoms, cohabitation with adult children for both partners), a husband's frailty was positively associated with his wife's frailty (odds ratio (OR) 3.34, 95% confidence interval (CI) 1.04-10.73, < 0.05), and a wife's frailty was significantly associated with her husband's frailty (OR 4.62, 95% CI 1.31-16.33, < 0.05), indicating a greater effect of the frailty status of the spouse among women than among men. Among the five components of the Fried frailty phenotype, weight loss, slowness, and exhaustion were the main contributing factors to the spousal association for frailty. In conclusion, having a frail spouse is a strong and independent risk factor for frailty among community-living older adults.

摘要

婚姻状况是身体脆弱的一个重要危险因素。然而,关于已婚夫妇之间身体脆弱的配偶一致性的数据有限。在这里,我们评估了由 Fried 脆弱表型和导致这种关联的特定表型成分定义的脆弱的配偶一致性。这项研究的数据来自韩国脆弱和衰老队列研究(KFACS),共纳入了 315 对年龄在 70 至 84 岁之间的已婚夫妇(630 人)。采用多变量逻辑回归进行分析。在调整了协变量(年龄、体重指数、教育程度、住房所有权、合并症、认知、抑郁症状、配偶与成年子女同住情况)后,丈夫的脆弱与妻子的脆弱呈正相关(比值比(OR)为 3.34,95%置信区间(CI)为 1.04-10.73,<0.05),妻子的脆弱与丈夫的脆弱显著相关(OR 为 4.62,95%CI 为 1.31-16.33,<0.05),表明女性脆弱配偶的脆弱状况对女性的影响大于男性。在 Fried 脆弱表型的五个组成部分中,体重减轻、行动缓慢和疲惫是导致脆弱的配偶相关性的主要因素。总之,有一个脆弱的配偶是社区居住的老年人脆弱的一个强烈和独立的危险因素。

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Korean frailty and aging cohort study (KFACS): cohort profile.
BMJ Open. 2020 Apr 22;10(4):e035573. doi: 10.1136/bmjopen-2019-035573.
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