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气溶胶传播 SARS-CoV-2 的风险、口罩的合理使用以及保护医护人员免受 COVID-19 感染。

Risk of SARS-CoV-2 transmission by aerosols, the rational use of masks, and protection of healthcare workers from COVID-19.

机构信息

Department of Infectious, Diseases and Hospital Hygiene, Freiburgstrasse, 3010, Bern, Switzerland.

Swissnoso, the National Center for Infection Control, Bern, Switzerland.

出版信息

Antimicrob Resist Infect Control. 2020 Jul 6;9(1):100. doi: 10.1186/s13756-020-00763-0.

Abstract

OBJECTIVES

To determine the risk of SARS-CoV-2 transmission by aerosols, to provide evidence on the rational use of masks, and to discuss additional measures important for the protection of healthcare workers from COVID-19.

METHODS

Literature review and expert opinion.

SHORT CONCLUSION

SARS-CoV-2, the pathogen causing COVID-19, is considered to be transmitted via droplets rather than aerosols, but droplets with strong directional airflow support may spread further than 2 m. High rates of COVID-19 infections in healthcare-workers (HCWs) have been reported from several countries. Respirators such as filtering face piece (FFP) 2 masks were designed to protect HCWs, while surgical masks were originally intended to protect patients (e.g., during surgery). Nevertheless, high quality standard surgical masks (type II/IIR according to European Norm EN 14683) appear to be as effective as FFP2 masks in preventing droplet-associated viral infections of HCWs as reported from influenza or SARS. So far, no head-to-head trials with these masks have been published for COVID-19. Neither mask type completely prevents transmission, which may be due to inappropriate handling and alternative transmission pathways. Therefore, compliance with a bundle of infection control measures including thorough hand hygiene is key. During high-risk procedures, both droplets and aerosols may be produced, reason why respirators are indicated for these interventions.

摘要

目的

确定 SARS-CoV-2 通过气溶胶传播的风险,为合理使用口罩提供证据,并讨论对保护医护人员免受 COVID-19 感染的其他重要措施。

方法

文献回顾和专家意见。

简短结论

导致 COVID-19 的病原体 SARS-CoV-2 被认为是通过飞沫传播,而不是通过气溶胶传播,但具有强定向气流的飞沫可能会传播得更远,超过 2 米。来自多个国家的报告显示,医护人员(HCWs)的 COVID-19 感染率很高。呼吸器(如过滤式面罩 (FFP) 2 口罩)旨在保护医护人员,而外科口罩最初旨在保护患者(例如,在手术期间)。然而,高质量标准的外科口罩(根据欧洲标准 EN 14683 为 II/IIR 型)似乎与 FFP2 口罩一样有效,可防止 HCWs 因飞沫引起的病毒感染,这在流感或 SARS 中都有报道。到目前为止,尚未为 COVID-19 发布这些口罩的头对头试验。这两种口罩类型都不能完全阻止传播,这可能是由于处理不当和其他传播途径造成的。因此,遵守包括彻底手部卫生在内的一整套感染控制措施是关键。在高风险手术中,飞沫和气溶胶都可能产生,这就是为什么这些干预措施需要使用呼吸器。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b91/7336662/30c662e866f6/13756_2020_763_Fig1_HTML.jpg

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