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重度肥胖对经耻骨后尿道中段吊带术长期成功率和并发症的影响。

Impact of severe obesity on long-term success and complications of the retropubic midurethral sling.

机构信息

Department of Obstetrics and Gynaecology, Middlemore Hospital, Auckland, New Zealand.

North Shore Hospital, Auckland, New Zealand.

出版信息

Int Urogynecol J. 2021 Jan;32(1):57-63. doi: 10.1007/s00192-020-04414-1. Epub 2020 Jul 6.

Abstract

INTRODUCTION AND HYPOTHESIS

With conflicting evidence in the literature, we hypothesised that the long-term subjective outcomes of the retropubic midurethral sling (MUS) are the same in the severely obese and non-obese populations.

METHODS

A retrospective matched cohort study was performed on women with a BMI ≥ 35 and < 30 who had a retropubic MUS placed between 2010 and 2015 using telephone questionnaires. The primary outcome was the success rate of surgery defined by the Urogenital Distress Inventory Short Form (UDI-6) stress subscale. Statistical analysis was performed to test for associations between primary and secondary outcomes across the two groups.

RESULTS

Seventy-eight severely obese (SOG) and 74 non-obese (NOG) were recruited. At a median time from surgery of 3.8 years the success rate was 47.4% in the SOG compared to 64.9% in the NOG (p = 0.03). There was a 22% reduction in the odds of success with every 5 unit increase in BMI (p = 0.03). There were higher rates of mixed urinary incontinence preoperatively (60.3% vs. 37.8%, p = 0.006) and persistent urinary urge incontinence postoperatively (48.7% vs. 32.4% p = 0.04) in the severely obese. Lower PGI-I scores were obtained in the severely obese group indicating less improvement in symptoms from surgery. There was no difference in complication rates between the groups.

CONCLUSION

Long-term subjective outcomes from the retropubic MUS are lower in severely obese women than in non-obese women with no difference in complication rates. High satisfaction and recommendation rates were found in both groups.

摘要

引言与假设

文献中存在相互矛盾的证据,因此我们假设,耻骨后尿道中段吊带(MUS)的长期主观结局在肥胖和非肥胖人群中是相同的。

方法

对 2010 年至 2015 年间因耻骨后 MUS 放置而接受电话问卷调查的 BMI≥35 和<30 的女性进行回顾性匹配队列研究。主要结局是尿失禁生活质量问卷(UDI-6)应激分量表定义的手术成功率。对两组间主要和次要结局进行统计学分析,以检验关联。

结果

共招募了 78 名重度肥胖(SOG)和 74 名非肥胖(NOG)女性。手术中位数为 3.8 年后,SOG 的成功率为 47.4%,NOG 为 64.9%(p=0.03)。BMI 每增加 5 个单位,手术成功率降低 22%(p=0.03)。SOG 组术前混合性尿失禁发生率较高(60.3% vs. 37.8%,p=0.006),术后持续性急迫性尿失禁发生率较高(48.7% vs. 32.4%,p=0.04)。SOG 组的 PGI-I 评分较低,表明手术对症状的改善较小。两组并发症发生率无差异。

结论

与非肥胖女性相比,耻骨后 MUS 的长期主观结局在肥胖女性中较低,但并发症发生率无差异。两组的满意度和推荐率均较高。

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