Department of Obstetrics and Gynaecology, Middlemore Hospital, Auckland, New Zealand.
North Shore Hospital, Auckland, New Zealand.
Int Urogynecol J. 2021 Jan;32(1):57-63. doi: 10.1007/s00192-020-04414-1. Epub 2020 Jul 6.
With conflicting evidence in the literature, we hypothesised that the long-term subjective outcomes of the retropubic midurethral sling (MUS) are the same in the severely obese and non-obese populations.
A retrospective matched cohort study was performed on women with a BMI ≥ 35 and < 30 who had a retropubic MUS placed between 2010 and 2015 using telephone questionnaires. The primary outcome was the success rate of surgery defined by the Urogenital Distress Inventory Short Form (UDI-6) stress subscale. Statistical analysis was performed to test for associations between primary and secondary outcomes across the two groups.
Seventy-eight severely obese (SOG) and 74 non-obese (NOG) were recruited. At a median time from surgery of 3.8 years the success rate was 47.4% in the SOG compared to 64.9% in the NOG (p = 0.03). There was a 22% reduction in the odds of success with every 5 unit increase in BMI (p = 0.03). There were higher rates of mixed urinary incontinence preoperatively (60.3% vs. 37.8%, p = 0.006) and persistent urinary urge incontinence postoperatively (48.7% vs. 32.4% p = 0.04) in the severely obese. Lower PGI-I scores were obtained in the severely obese group indicating less improvement in symptoms from surgery. There was no difference in complication rates between the groups.
Long-term subjective outcomes from the retropubic MUS are lower in severely obese women than in non-obese women with no difference in complication rates. High satisfaction and recommendation rates were found in both groups.
文献中存在相互矛盾的证据,因此我们假设,耻骨后尿道中段吊带(MUS)的长期主观结局在肥胖和非肥胖人群中是相同的。
对 2010 年至 2015 年间因耻骨后 MUS 放置而接受电话问卷调查的 BMI≥35 和<30 的女性进行回顾性匹配队列研究。主要结局是尿失禁生活质量问卷(UDI-6)应激分量表定义的手术成功率。对两组间主要和次要结局进行统计学分析,以检验关联。
共招募了 78 名重度肥胖(SOG)和 74 名非肥胖(NOG)女性。手术中位数为 3.8 年后,SOG 的成功率为 47.4%,NOG 为 64.9%(p=0.03)。BMI 每增加 5 个单位,手术成功率降低 22%(p=0.03)。SOG 组术前混合性尿失禁发生率较高(60.3% vs. 37.8%,p=0.006),术后持续性急迫性尿失禁发生率较高(48.7% vs. 32.4%,p=0.04)。SOG 组的 PGI-I 评分较低,表明手术对症状的改善较小。两组并发症发生率无差异。
与非肥胖女性相比,耻骨后 MUS 的长期主观结局在肥胖女性中较低,但并发症发生率无差异。两组的满意度和推荐率均较高。