UOC Neurologia - Dipartimento Scienze dell'Invecchiamento, Neurologiche, Ortopediche e della Testa-Collo, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Università Cattolica del Sacro Cuore, Largo Francesco Vito, 1, 00168, Rome, Italy.
Neurol Sci. 2020 Sep;41(9):2309-2313. doi: 10.1007/s10072-020-04545-9. Epub 2020 Jul 6.
To evaluate the impact of the lockdown measures, consequent to the outbreak of COVID-19 pandemic, on the quality of pre-hospital and in-hospital care of patients with acute ischemic stroke.
This is an observational cohort study. Data sources were the clinical reports of patients admitted during the first month of lockdown and discharged with a confirmed diagnosis of stroke or TIA. Data were collected in the interval ranging from March 11th to April 11th 2020. As controls, we evaluated the clinical reports of patients with stroke or TIA admitted in the same period of 2019.
The clinical reports of patients eligible for the study were 52 in 2020 (71.6 ± 12.2 years) and 41 in 2019 (73.7 ± 13.1 years). During the lockdown, we observed a significant increase in onset-to-door time (median = 387 vs 161 min, p = 0.001), a significant reduction of the total number of thrombolysis (7 vs 13, p = 0.033), a non-significant increase of thrombectomy (15 vs 9, p = 0.451), and a significant increase in door-to-groin time (median = 120 vs 93 min, p = 0.048). No relevant difference was observed between 2019 and 2020 in the total number of patients admitted.
Due to the COVID-19 pandemic and lockdown measures, the stroke care pathway changed, involving both pre-hospital and in-hospital performances.
评估 COVID-19 大流行爆发后实施的封锁措施对急性缺血性脑卒中患者的院前和院内治疗质量的影响。
这是一项观察性队列研究。资料来源为封锁期间第一个月内入院并确诊为卒中或 TIA 出院患者的临床报告。数据收集时间为 2020 年 3 月 11 日至 4 月 11 日。作为对照，我们评估了 2019 年同期入院的卒中或 TIA 患者的临床报告。
符合研究条件的患者临床报告共 52 份（2020 年，71.6±12.2 岁；2019 年，41 份，73.7±13.1 岁）。在封锁期间，我们观察到发病至门时间明显延长（中位数分别为 387 分钟和 161 分钟，p=0.001），溶栓总数显著减少（7 例和 13 例，p=0.033），取栓术无显著增加（15 例和 9 例，p=0.451），门至股动脉时间明显延长（中位数分别为 120 分钟和 93 分钟，p=0.048）。2019 年和 2020 年入院患者总数无显著差异。
由于 COVID-19 大流行和封锁措施，卒中治疗途径发生了变化，涉及院前和院内表现。
