Daw Mohamed Ali, Daw Amina Mohamed, Sifennasr Nadia Emhemed Mohamed, Draha Aisha, Daw Ahmed, Daw Ali, Ahmed Mohamed, Mokhtar Ebtisam, El-Bouzedi Abdallah, Daw Ibrahem, Adam Samia, Warrag Saed
Department of Medical Microbiology & Immunology, Faculty of Medicine, University of Tripoli, CC 82668, Tripoli, Libya.
Department of General Medicine, Faculty of Medicine, University of Tripoli, CC 82668, Tripoli, Libya.
Pan Afr Med J. 2020 Apr 14;35:120. doi: 10.11604/pamj.2020.35.120.20055. eCollection 2020.
North Africa is known to be endemic for hepatitis D virus. However, data one the prevalence of this virus in Libya are scanty. This study aimed to determine the prevalence of hepatitis D virus infection in Libya and analyze the demographic factors associated with the infection, and also to assess the variations across the regions and districts.
A total of 1873 samples collected from all over the country were tested for antibodies against hepatitis B surface antigen and the results were correlated with demographic and geographic variables.
The overall prevalence of hepatitis D virus infection was 1.7%. The prevalence rate was significantly high among those aged over 40 years (P < 0.001) and it was associated with intravenous drug use and coinfection with human immunodeficiency virus and/or hepatitis C virus infection (P < 0.001). The prevalence rates varied with geographic location and differed markedly within the regions the country. The highest rate reported was in the central region of Libya, followed by the western and eastern regions.
Hepatitis D virus infection rate in Libya is considered to be low but is of some concern in some districts. This has been propagated by population displacement and African immigrants, indicating that a continuous epidemiological surveillance program should be implemented.
众所周知，北非是丁型肝炎病毒的地方性流行区。然而，关于该病毒在利比亚流行情况的数据却很少。本研究旨在确定利比亚丁型肝炎病毒感染的流行率，分析与感染相关的人口统计学因素，并评估各地区之间的差异。
对从全国各地收集的1873份样本进行乙型肝炎表面抗原抗体检测，并将结果与人口统计学和地理变量相关联。
丁型肝炎病毒感染的总体流行率为1.7%。40岁以上人群的流行率显著较高（P < 0.001），且与静脉注射吸毒以及与人类免疫缺陷病毒和/或丙型肝炎病毒合并感染有关（P < 0.001）。流行率因地理位置而异，在该国各地区之间差异明显。报告的最高流行率出现在利比亚中部地区，其次是西部地区和东部地区。
利比亚的丁型肝炎病毒感染率被认为较低，但在一些地区令人担忧。这是由人口流离失所和非洲移民传播的，表明应实施持续的流行病学监测计划。
