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利加隆(LGD-4033)诱导的肝损伤。

Ligandrol (LGD-4033)-Induced Liver Injury.

作者信息

Barbara Mary, Dhingra Sadhna, Mindikoglu Ayse L

机构信息

Section of Gastroenterology and Hepatology, Margaret M. and Albert B. Alkek Department of Medicine, Baylor College of Medicine, Houston, TX.

Division of Abdominal Transplantation, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX.

出版信息

ACG Case Rep J. 2020 Jun 11;7(6):e00370. doi: 10.14309/crj.0000000000000370. eCollection 2020 Jun.

Abstract

We described a 32-year-old man who developed severe drug-induced liver injury after using Ligandrol (LGD-4033). The diagnosis was confirmed by a liver biopsy that showed cholestatic hepatitis with a mild portal, periportal, and perisinusoidal fibrosis. Ligandrol is a selective androgen receptor modulator that is available over the counter and via the internet.

摘要

我们描述了一名32岁男性,他在使用Ligandrol(LGD - 4033)后出现了严重的药物性肝损伤。肝活检证实了诊断,活检显示胆汁淤积性肝炎伴轻度门静脉、汇管区周围和窦周纤维化。Ligandrol是一种选择性雄激素受体调节剂,可在柜台及通过互联网购得。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0856/7304490/b37aa3a1b7c5/ac9-7-e00370-g001.jpg

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