Antonaci S, Jirillo E, Garofalo A R, Polignano A, Resta F, Pugliese P, Capurso A, Bonomo L
Fisiopatologia Medica, University of Bari Medical School, Italy.
Cytobios. 1988;54(218-219):181-9.
Plasma lipoproteins inhibit immune function. Polymorphonuclear cell (PMN) and monocyte activities, and pokeweed mitogen (PWM)-driven B cell differentiation in patients with type IIa, type IIb and type IV primary hyperlipoproteinaemia were evaluated. Evidence is provided for a selective impairment of these functional capacities in type IIa and type IIb hyperlipoproteinaemic patients, while immune responsiveness is unaffected in type IV primary hyperlipoproteinaemia. The data suggest a specific immune dysfunction in patients with type IIa and type IIb primary hyperlipoproteinaemia.
血浆脂蛋白会抑制免疫功能。对IIa型、IIb型和IV型原发性高脂血症患者的多形核细胞（PMN）和单核细胞活性以及商陆丝裂原（PWM）驱动的B细胞分化进行了评估。有证据表明，IIa型和IIb型高脂血症患者的这些功能能力存在选择性损害，而IV型原发性高脂血症患者的免疫反应性未受影响。数据表明，IIa型和IIb型原发性高脂血症患者存在特定的免疫功能障碍。
