Department of Clinical Haematology, NHS Foundation Trust, Guy's and St Thomas, London, UK.
Viapath Analytics LLP, St Thomas Hospital, London, UK.
Br J Haematol. 2020 Nov;191(3):382-385. doi: 10.1111/bjh.17007. Epub 2020 Oct 21.
There has been a significant surge in admissions to critical care during the coronavirus disease 2019 (COVID-19) pandemic. At present, the demands on blood components have not been described. We reviewed their use during the first 6 weeks of the outbreak from 3 March 2020 in a tertiary-level critical care department providing venovenous extracorporeal membrane oxygenation (vv-ECMO). A total of 265 patients were reviewed, with 235 not requiring ECMO and 30 requiring vv-ECMO. In total, 50 patients required blood components during their critical care admission. Red cell concentrates were the most frequently transfused component in COVID-19-infected patients with higher rates of use during vv-ECMO. The use of fresh frozen plasma, cryoprecipitate and platelet transfusions was low in a period prior to the use of convalescent plasma.
在 2019 冠状病毒病(COVID-19)大流行期间,重症监护病房的入院人数显著增加。目前,尚未描述血液成分的需求。我们回顾了从 2020 年 3 月 3 日起在一家提供静脉-静脉体外膜肺氧合(vv-ECMO)的三级重症监护病房爆发的头 6 周内的使用情况。共回顾了 265 例患者,其中 235 例不需要 ECMO,30 例需要 vv-ECMO。在重症监护期间,共有 50 名患者需要血液成分。红细胞浓缩物是 COVID-19 感染患者中最常输注的成分,在使用 vv-ECMO 期间使用率更高。在使用恢复期血浆之前,新鲜冷冻血浆、冷沉淀和血小板输注的使用率较低。