Dangor Y, Miller S D, Exposto F da L, Koornhof H J
Emergent Pathogen Research Unit, South African Medical Research Council, Johannesburg.
Antimicrob Agents Chemother. 1988 Sep;32(9):1458-60. doi: 10.1128/AAC.32.9.1458.
We determined the antimicrobial susceptibilities of 122 recent clinical isolates of Haemophilus ducreyi to 24 antimicrobial agents. All isolates produced beta-lactamase and were resistant to penicillins. The majority of strains were also resistant to tetracycline, doxycycline, and sulfamethoxazole. All isolates were susceptible to macrolides, quinolones, extended-spectrum cephalosporins, spectinomycin, rifampin, and amoxycillin-clavulanate. Reduced susceptibility to minocycline, co-trimoxazole, and kanamycin was noted. Chloramphenicol and thiamphenicol resistance was noted for the first time among southern African strains.
我们测定了122株近期分离的杜克雷嗜血杆菌临床菌株对24种抗菌药物的敏感性。所有分离株均产生β-内酰胺酶,对青霉素耐药。大多数菌株还对四环素、强力霉素和磺胺甲恶唑耐药。所有分离株对大环内酯类、喹诺酮类、广谱头孢菌素、壮观霉素、利福平和阿莫西林-克拉维酸敏感。注意到对米诺环素、复方新诺明和卡那霉素的敏感性降低。在南部非洲菌株中首次发现对氯霉素和甲砜霉素耐药。