He Andong, Zhou Yixuan, Wei Yiling, Li Ruiman
Obstetrics and Gynecology, The First Affiliated Hospital of Jinan University, Guangzhou, CHN.
Obstetrics and Gynecology, The First Affiliate Hospital of Jinan University, Guangzhou, CHN.
Cureus. 2020 Jun 30;12(6):e8925. doi: 10.7759/cureus.8925.
To date, the etiology of preeclampsia (PE) has not been clarified and the specific treatment is lacking; hence, early prediction and prevention are very important. Thus, a large number of biomarkers that may be associated with PE have been identified based on proteomics to provide a reference for the prediction of PE and for the understanding of the pathological mechanisms of this disease. This article briefly summarizes the application of proteomics in PE and the potential protein biomarkers to provide a reference for other researchers.
迄今为止，子痫前期（PE）的病因尚未阐明，且缺乏特效治疗方法；因此，早期预测和预防非常重要。基于蛋白质组学，大量可能与PE相关的生物标志物已被鉴定出来，为PE的预测及该疾病病理机制的理解提供参考。本文简要总结蛋白质组学在PE中的应用以及潜在的蛋白质生物标志物，为其他研究人员提供参考。
