Attom Saeed, Alzomor Omar
Pediatric Department, Al Mukala University Hospital, Al Mukala, Yemen.
Pediatric Infectious Diseases Section, Children Hospital, King Saud Medical City, Riyadh, Saudi Arabia.
Int J Pediatr Adolesc Med. 2020 Jun;7(2):98-99. doi: 10.1016/j.ijpam.2019.10.004. Epub 2019 Oct 15.
Unreported cases of diphtheria are still present in developing countries. A 9-year-old incompletely vaccinated girl was admitted with pharyngotonsillitis caused by diphtheria. On day 9 of her illness, renal and cardiac failure occurred. Unfortunately, she died within hours of admission to intensive care with cardiogenic shock despite the vigorous supportive care delivered to her and the administration of antibiotics and diphtheria antitoxin. The suboptimal dose of antitoxin administered initially upon admission to hospital was likely to have contributed to the unfavorable outcome.
发展中国家仍存在未报告的白喉病例。一名9岁未完全接种疫苗的女孩因白喉引起的咽扁桃体炎入院。在患病第9天,出现了肾衰竭和心力衰竭。不幸的是,尽管对她进行了积极的支持治疗并给予了抗生素和白喉抗毒素,但她在入住重症监护病房数小时内死于心源性休克。入院时最初给予的抗毒素剂量不足可能导致了不良后果。