Mazhangara Irene Rumbidzai, Masika Patrick Julius, Mupangwa John Fisher, Chivandi Eliton, Jaja Ishmael Festus, Muchenje Voster
University of Fort Hare, Department of Livestock and Pasture Science, P/Bag X1314, Alice 5700, South Africa.
Fort Cox College of Agriculture and Forestry, P.O. Box 2187, King William's Town, 5600, South Africa.
Parasite Epidemiol Control. 2020 Jun 6;10:e00157. doi: 10.1016/j.parepi.2020.e00157. eCollection 2020 Aug.
is a medicinally important plant whose roots are used to control gastrointestinal parasites in goats. The use of plant-based anthelmintics as potential alternatives to synthetic anthelmintics in controlling gastrointestinal worms in ruminants is a promising area of research. The study was carried out to ascertain the efficacy of . in controlling goat trematodes. Standard procedures were used to quantify the phytochemicals in the water, ethanol and methanol root extracts of . . The quantitative phytochemical analysis revealed that alkaloids (93.24 ± 1.68%), condensed tannins (450.52 ± 0.15 mg CE/g), flavonoids (803.93 ± 0.13 mg QE/g), phenols (476.11 ± 0.37 mg GAE/g) and saponins (83.28 ± 1.72%) were present in . root extracts. adult worms recovered from the rumen of freshly slaughtered goats were used. screening of ethanol, methanol and water extracts of . for potential anthelmintic activity against adult . worm motility showed time and dose-dependent significant effects. Ethanol extracts showed a highly significant ( < .) inhibition of motility (86.67 and 96.67%) at concentrations 7.5 and 15 mg/mL respectively, after 12 h of treatment, while methanol and water extracts exhibited a significant ( < .) inhibition of motility (96.67 and 66.67% respectively) at concentration of 15 mg/mL 16 h post-exposure. Our findings confirm the efficacy of . in controlling goat trematodes.
是一种具有重要药用价值的植物,其根可用于控制山羊体内的胃肠道寄生虫。在反刍动物中,使用植物性驱虫剂作为合成驱虫剂控制胃肠道蠕虫的潜在替代品是一个很有前景的研究领域。本研究旨在确定……在控制山羊吸虫方面的功效。采用标准程序对……根的水提取物、乙醇提取物和甲醇提取物中的植物化学物质进行定量分析。定量植物化学分析表明,……根提取物中含有生物碱(93.24±1.68%)、缩合单宁(450.52±0.15毫克CE/克)、黄酮类化合物(803.93±0.13毫克QE/克)、酚类(476.11±0.37毫克GAE/克)和皂苷(83.28±1.72%)。使用从刚宰杀山羊的瘤胃中回收的成虫。对……的乙醇提取物、甲醇提取物和水提取物进行筛选,以检测其对成虫……蠕虫运动的潜在驱虫活性,结果显示时间和剂量依赖性显著影响。乙醇提取物在处理12小时后,浓度分别为7.5和15毫克/毫升时,对运动的抑制作用极显著(P<0.01)(分别为86.67%和96.67%),而甲醇提取物和水提取物在暴露16小时后,浓度为15毫克/毫升时,对运动的抑制作用显著(P<0.05)(分别为96.67%和66.67%)。我们的研究结果证实了……在控制山羊吸虫方面的功效。