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估算无偏头痛生活带来的节省:西班牙地图集的结果。

Estimating the savings associated with a migraine-free life: results from the Spanish Atlas.

作者信息

Irimia P, Garrido-Cumbrera M, Santos-Lasaosa S, Braçe O, Colomina I, Blanch C, Pozo-Rosich P

机构信息

Neurology Department, Clínica Universidad de Navarra, Pamplona, Spain.

Navarra's Health Research Institute (IDISNA), Pamplona, Spain.

出版信息

Eur J Neurol. 2020 Dec;27(12):2616-2624. doi: 10.1111/ene.14431. Epub 2020 Aug 8.

Abstract

BACKGROUND AND PURPOSE

Migraine is a common and costly neurological disorder. The aims of this study were to quantify the costs of chronic (CM) and episodic migraine (EM) in Spain, evaluating the impact of psychiatric comorbidities and disability, and to estimate the economic savings associated with reducing the number of migraine-days by 50%.

METHODS

This was an observational, cross-sectional analysis of data from migraine patients who participated in the Spanish Migraine Atlas. The participants were invited to complete a structured questionnaire including the following scales: the Headache Needs Assessment, the Hospital Anxiety and Depression Scale, and the Migraine Disability Assessment Scale (MIDAS).

RESULTS

A total of 475 patients were included, of whom 187 had CM (39.4%). Total costs per patient/year were: €16 578.2 ± €34 568.1 for CM and €6227.8 ± €6515.7 for EM. A higher degree of disability, according to MIDAS, significantly increased the total cost of migraine, while the presence of psychiatric comorbidity increased costs for EM patients only. A reduction of 1 migraine-day per month decreased average total costs by €744.14 per patient/year for EM and €663.20 per patient/year for CM, while a reduction in the number of migraine-days by 50% would result in economic savings of €2232.44 per patient/year (R  = 0.927) for EM and €6631.99 per patient/year (R  = 0.886) for CM.

CONCLUSIONS

The costs associated with migraine were driven by migraine frequency and the degree of disability, whereas psychiatric comorbidity only influenced the cost of EM. These results highlight the need to optimize migraine management to reduce the economic migraine burden. Future studies are needed to confirm our results.

摘要

背景与目的

偏头痛是一种常见且代价高昂的神经系统疾病。本研究的目的是量化西班牙慢性偏头痛(CM)和发作性偏头痛(EM)的成本,评估精神疾病共病和残疾的影响,并估计将偏头痛天数减少50%所带来的经济节省。

方法

这是一项对参与西班牙偏头痛地图集的偏头痛患者数据进行的观察性横断面分析。邀请参与者完成一份结构化问卷,包括以下量表:头痛需求评估、医院焦虑抑郁量表和偏头痛残疾评估量表(MIDAS)。

结果

共纳入475例患者,其中187例为慢性偏头痛(39.4%)。每位患者每年的总成本为:慢性偏头痛患者为16578.2±34568.1欧元,发作性偏头痛患者为6227.8±6515.7欧元。根据MIDAS,更高程度的残疾显著增加了偏头痛的总成本,而精神疾病共病仅增加了发作性偏头痛患者的成本。每月减少1个偏头痛日,发作性偏头痛患者平均每年总成本降低744.14欧元,慢性偏头痛患者平均每年总成本降低663.20欧元,而偏头痛天数减少50%将使发作性偏头痛患者每年节省2232.44欧元(R=0.927),慢性偏头痛患者每年节省6631.99欧元(R=0.886)。

结论

偏头痛相关成本由偏头痛发作频率和残疾程度驱动,而精神疾病共病仅影响发作性偏头痛的成本。这些结果凸显了优化偏头痛管理以减轻偏头痛经济负担的必要性。需要进一步的研究来证实我们的结果。

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