Pascual Julio, Núñez Mercedes, Panni Tommaso, Díaz-Cerezo Silvia, Novick Diego, Ciudad Antonio
Hospital Universitario Marqués de Valdecilla, Universidad de Cantabria and IDIVAL, Santander, Spain.
Eli Lilly and Company, Avenida de La Industria 30, Alcobendas, 28108, Madrid, Spain.
Pain Ther. 2023 Oct;12(5):1209-1220. doi: 10.1007/s40122-023-00538-6. Epub 2023 Jul 16.
This analysis aimed to evaluate demographics, migraine-related disability, symptoms, diagnosis and healthcare consultation, work productivity, and treatment patterns according to headache frequency in adults with migraine in the OVERCOME (ObserVational survey of the Epidemiology, tReatment and Care Of MigrainE) (Spain) study.
Data were obtained from an observational, cross-sectional, web-based survey conducted between October 2020-February 2021 in Spain. Eligible participants were adult members of online survey panels living in Spain who were able to read and write Spanish and fulfilled the International Classification of Headache Disorders, third edition (ICHD-3) criteria for migraine or had a self-reported physician diagnosis.
In total, 10,229 patients comprised the Spanish sample. Only 56.2% of respondents had a confirmed healthcare professional (HCP) diagnosis of migraine, despite almost all meeting modified ICHD-3 criteria. Pain severity, migraine-related disability, and interictal burden increased with increasing number of headache days per month. Migraine impacted on respondents' work productivity, with increases in presenteeism, work productivity loss, and daily activity impairment at higher headache frequencies. Over the past year, 66.2% of all HCP visits were specifically due to migraine, most commonly with a general practitioner or pharmacist. A subgroup of 1277 patients (12.5% of the total survey population) met eligibility criteria for migraine preventive medications, of whom only 36.6% were currently taking a preventive.
Results of the OVERCOME (Spain) survey reveal the substantial burden of migraine, which is directly linked to headache frequency. However, most patients experiencing frequent headaches and eligible for migraine preventives are currently not taking them. Findings highlight the importance of addressing unmet needs for people with migraine in Spain.
本分析旨在根据“战胜偏头痛（OVERCOME）（西班牙）研究”中偏头痛成人患者的头痛频率，评估其人口统计学特征、偏头痛相关残疾、症状、诊断与医疗咨询、工作生产力以及治疗模式。
数据来自于2020年10月至2021年2月在西班牙开展的一项基于网络的观察性横断面调查。符合条件的参与者是居住在西班牙的在线调查小组成年成员，他们能够读写西班牙语，且符合《国际头痛疾病分类》第三版（ICHD - 3）偏头痛标准或有医生自我报告诊断。
西班牙样本共有10229名患者。尽管几乎所有受访者都符合修订后的ICHD - 3标准，但只有56.2%的受访者得到了医疗保健专业人员（HCP）确诊的偏头痛诊断。疼痛严重程度、偏头痛相关残疾以及发作间期负担随每月头痛天数增加而加重。偏头痛影响了受访者的工作生产力，头痛频率越高，出勤主义、工作生产力损失和日常活动受损情况越严重。在过去一年中，所有HCP就诊中有66.2%专门是由于偏头痛，最常见的是看全科医生或药剂师。1277名患者亚组（占总调查人群的12.5%）符合偏头痛预防性药物的资格标准，其中目前只有36.6%的人正在服用预防性药物。
“战胜偏头痛（西班牙）”调查结果揭示了偏头痛的沉重负担，这与头痛频率直接相关。然而，大多数有频繁头痛且符合偏头痛预防性药物使用条件的患者目前并未服用。研究结果凸显了满足西班牙偏头痛患者未满足需求的重要性。
