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Elevated levels of interleukin 2 receptor in sera of patients with atopic dermatitis and psoriasis.

作者信息

Kapp A, Piskorski A, Schöpf E

机构信息

Department of Dermatology, University of Freiburg, F.R.G.

出版信息

Br J Dermatol. 1988 Dec;119(6):707-10. doi: 10.1111/j.1365-2133.1988.tb03491.x.

DOI:10.1111/j.1365-2133.1988.tb03491.x
PMID:3264510
Abstract

Elevated levels of serum interleukin 2 receptor (IL2R) represent an early measure of T cell activation. The concentration of IL2R was measured in the sera of patients with atopic dermatitis (n = 58) or psoriasis, without psoriatic arthritis, (n = 26), who had moderate to severe disease activity, and in non-atopic healthy controls (n = 37) by an ELISA technique. Serum IL2R levels were found to be significantly elevated in both disease groups compared with the controls. The increase in serum IL2R may be due to T cell activation in the dermis.

摘要

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