Department of Public Health, Health Sciences Research Institute, College of Social Sciences, Humanities, and Arts, University of California, Merced, CA 95343, USA.
Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD 20892, USA.
Int J Environ Res Public Health. 2020 Jul 7;17(13):4888. doi: 10.3390/ijerph17134888.
: We monitored exposure to fine particulates (PM), ozone, nitrogen dioxide (NO), and ambient temperature for pregnant women with and without asthma. : Women ( = 40) from the Breathe-Well-Being, Environment, Lifestyle, and Lung Function Study (2015-2018) were enrolled during pregnancy and monitored for 2-4 days. Daily pollutants were measured using personal air monitors, indoor air monitors, and nearest Environmental Protection Agency's stationary monitors based on GPS tracking and home address. : Personal-monitor measurements of PM, ozone, and NO did not vary by asthma status but exposure profiles significantly differed by assessment methods. EPA stationary monitor-based methods appeared to underestimate PM and temperature exposure and overestimate ozone and NO exposure. Higher indoor-monitored PM exposures were associated with smoking and the use of gas appliances. The proportion of waking-time during which personal monitors were worn was ~56%. Lower compliance was associated with exercise, smoking, being around a smoker, and the use of a prescription drug. : Exposure did not vary by asthma status but was influenced by daily activities and assessment methods. Personal monitors may better capture exposures but non-compliance merits attention. Meanwhile, larger monitoring studies are warranted to further understand exposure profiles and the health effects of air pollution during pregnancy.
我们监测了哮喘孕妇和非哮喘孕妇的细颗粒物(PM)、臭氧、二氧化氮(NO)和环境温度暴露情况。
来自“呼吸健康、环境、生活方式和肺功能研究”(2015-2018 年)的 40 名女性在怀孕期间被纳入研究,并监测了 2-4 天。每日污染物使用个人空气监测器、室内空气监测器和基于 GPS 跟踪和家庭住址的最近环境保护局固定监测器进行测量。
个人监测器测量的 PM、臭氧和 NO 与哮喘状况无关,但评估方法显著不同。基于 EPA 固定监测器的方法似乎低估了 PM 和温度暴露,高估了臭氧和 NO 暴露。更高的室内监测 PM 暴露与吸烟和使用燃气器具有关。佩戴个人监测器的清醒时间比例约为 56%。较低的依从性与运动、吸烟、周围有人吸烟以及使用处方药物有关。
暴露情况不因哮喘状况而异,但受日常活动和评估方法的影响。个人监测器可能更好地捕捉暴露情况,但需要注意不依从性问题。同时,需要进行更大规模的监测研究,以进一步了解怀孕期间的暴露情况和空气污染对健康的影响。