Prevalence of xerophthalmia in relation to nutrition and general health in preschool-age children in three regions of Tanzania.

Integrated nutrition/health surveys were carried out in Mbeya, Iringa and Kagera Regions in Tanzania in which a total of 12,880 children were examined for the presence of xerophthalmia. Xerophthalmia was found to be a problem of public health significance in two of the three regions surveyed where the prevalence of active corneal xerophthalmic lesions was above the criteria set by WHO. Because of clustering of the children with Bitot's spots, corneal xerosis/ulceration and corneal scarring, only certain villages or groups of villages could be regarded as areas where xerophthalmia is a problem. The results of the ophthalmological examinations are discussed in relation to the nutritional status of the children as measured by anthropometric indices, serum levels of retinol-binding protein and prealbumin, haematological parameters, and vaccination status.