Zhang Jian-Wei, Liu Nai-Gang
Department of Acupuncture and Moxibustion, Weifang Traditional Chinese Hospital, Weifang 261041, Shandong Province, China.
Department of Acupuncture and Moxibustion, China-Japan Friendship Hospital.
Zhongguo Zhen Jiu. 2020 Jul 12;40(7):731-5. doi: 10.13703/j.0255-2930.20190706-0001.
To observe the clinical effect of needle-knife at cervical spine area as adjunctive therapy on dry eye syndrome.
A total of 84 patients with dry eye syndrome were randomized into 3 groups, named group A, group B and group C, 28 cases in each one (1 case dropped off in the group A, 2 cases dropped off in both group B and C). In the group A, needle-knife was applied at the margo inferior of external occipital protuberance, the range of 4 cm bilateral to external occipital protuberance, the spinous process of C, the range of 3 cm bilateral to 2 cm above C spinous process, the range of 2 cm bilateral to C, C, C spinous process for once a week; acupuncture was applied at Jingming (BL 1), Cuanzhu (BL 2), Zusanli (ST 36), Sanyinjiao (SP 6), Taixi (KI 3), Yanglao (SI 6), Ganshu (BL 18), Shenshu (BL 23), etc. for once a day, 6 times a week; sodium hyaluronate eye drop was given one drop once, 5-6 times a day. Treatment of acupuncture and sodium hyaluronate eye drop was given in the group B, sodium hyaluronate eye drop was given in the group C, the acupoints selection and the manipulation of acupuncture, the dosage of sodium hyaluronate eye drop were the same as the group A. One week was as one course and 3 courses were required in the 3 groups. SchirmerⅠtest (SⅠT), break-up time (BUT), scores of corneal fluorescein staining (CFS) and eye symptom before and after treatment were observed, the clinical effect was evaluated in the 3 groups.
SⅠT was increased, BUT was prolonged, scores of CFS and eye symptom were reduced after treatment in the group A and group B (<0.01); scores of CFS and eye symptom were reduced after treatment in the group C (<0.01). The variations of SⅠT, BUT and the scores of CFS and eye symptom in the group A were greater than those in the group B and the group C (<0.01); the variations of above indexes in the group B were greater than those in the group C (<0.05, <0.01). The total effective rate was 94.4% (51/54) in the group A, which was superior to 78.8% (41/52) in the group B and 48.1% (25/52) in the group C (<0.01), and the total effective rate in the group B was superior to the group C (<0.01).
Needle-knife at cervical spine area as adjunctive therapy can relieve the clinical symptoms and improve the function of lacrimal gland in patients with dry eye syndrome.
观察针刀在颈椎区域辅助治疗干眼症的临床疗效。
84例干眼症患者随机分为A、B、C三组，每组28例（A组脱落1例，B组和C组各脱落2例）。A组于枕外隆凸下缘、枕外隆凸双侧4 cm范围、C棘突、C棘突上方2 cm双侧3 cm范围、C、C、C棘突双侧2 cm范围行针刀治疗，每周1次；针刺睛明（BL 1）、攒竹（BL 2）、足三里（ST 36）、三阴交（SP 6）、太溪（KI 3）、养老（SI 6）、肝俞（BL 18）、肾俞（BL 23）等穴位，每日1次，每周6次；给予透明质酸钠滴眼液，每次1滴，每日5 - 6次。B组给予针刺和透明质酸钠滴眼液治疗，C组仅给予透明质酸钠滴眼液治疗，针刺穴位选择、手法及透明质酸钠滴眼液用量同A组。3组均以1周为1个疗程，共治疗3个疗程。观察治疗前后泪液分泌试验（SⅠT）、泪膜破裂时间（BUT）、角膜荧光素染色（CFS）评分及眼部症状，评价3组临床疗效。
A组和B组治疗后SⅠT升高，BUT延长，CFS评分及眼部症状减轻（<0.01）；C组治疗后CFS评分及眼部症状减轻（<0.01）。A组SⅠT、BUT及CFS评分和眼部症状的变化幅度大于B组和C组（<0.01）；B组上述指标变化幅度大于C组（<0.05，<0.01）。A组总有效率为94.4%（51/54），优于B组的78.8%（41/52）和C组的48.1%（25/52）（<0.01），且B组总有效率优于C组（<0.01）。
颈椎区域针刀辅助治疗可缓解干眼症患者临床症状，改善泪腺功能。
