Zhou Ting, Zhu Dan, Xu Xin-Yin, Luo Zhi-Hui, Gu Xiao-Lei, Chen Jia, Chen Zi-Qin, Chen Bei, Zhang Yan-Lin, Wang Kun-Xiu, Yan Peng, Chen Song
College of Acupuncture and Orthopedics, Hubei University of CM, Wuhan 430061, China.
Department of Ophthalmology, Hubei Provincial Hospital of TCM.
Zhongguo Zhen Jiu. 2022 Oct 12;42(10):1120-4. doi: 10.13703/j.0255-2930.20211030-0001.
To compare the clinical efficacy of thumb-tack needle and sodium hyaluronate eye drops for dry eye.
A total of 60 patients with dry eye were randomly divided into a thumb-tack needle group and a western medication group, 30 cases in each group. Based on theory, thumb-tack needle was applied at Zhiyin (BL 67), Lidui (ST 45), Fuyang (BL 59), Yanglao (SI 6), Jingming (BL 1) and Cuanzhu (BL 2) in the thumb-tack needle group, 2 times a week. In the western medication group, 0.1% sodium hyaluronate eye drops were applied, 3 times a day. Both groups were treated for 4 weeks. Before and after treatment, TCM symptom score, tear film break-up time (BUT), SchirmerⅠtest (SⅠT), corneal fluorescein sodium staining (FL) score and 36-item short form health survey (SF-36) score were observed, and the clinical efficacy was evaluated in the two groups.
After treatment, the total scores and each item score of TCM symptom in the two groups were decreased compared with before treatment (<0.05); except for score of visual fatigue and photophobia, the total score and each item score of TCM symptom in the thumb-tack needle group were lower than the western medication group (<0.05). After treatment, the BUT, SⅠT and SF-36 scores were increased and the FL scores were decreased in the two groups (<0.05); the BUT, SⅠT and SF-36 score were higher than the western medication group (<0.05), and the FL score was lower than the western medication group (<0.05) in the thumb-tack needle group. The total effective rate in the thumb-tack needle group was 93.3% (28/30), which was higher than 80.0% (24/30) in the western medication group (<0.05).
Thumb-tack needle based on theory could effectively relieve clinical symptoms of dry eye patients, prolong tear film break-up time, increase tear secretion, improve tear film function and quality of life, and its curative effect is better than sodium hyaluronate eye drops.
比较揿针与透明质酸钠滴眼液治疗干眼症的临床疗效。
将60例干眼症患者随机分为揿针组和西药组，每组30例。揿针组依据理论，选取至阴（BL 67）、厉兑（ST 45）、跗阳（BL 59）、养老（SI 6）、睛明（BL 1）和攒竹（BL 2）进行揿针治疗，每周2次。西药组应用0.1%透明质酸钠滴眼液，每日3次。两组均治疗4周。观察治疗前后中医症状评分、泪膜破裂时间（BUT）、泪液分泌试验（SⅠT）、角膜荧光素钠染色（FL）评分及36条目简明健康状况调查量表（SF - 36）评分，并评价两组临床疗效。
治疗后，两组中医症状总分及各条目评分均较治疗前降低（<0.05）；除视疲劳、畏光评分外，揿针组中医症状总分及各条目评分低于西药组（<0.05）。治疗后，两组BUT、SⅠT及SF - 36评分升高，FL评分降低（<0.05）；揿针组BUT、SⅠT及SF - 36评分高于西药组（<0.05），FL评分低于西药组（<0.05）。揿针组总有效率为93.3%（28/30），高于西药组的80.0%（24/30）（<0.05）。
基于理论的揿针能有效缓解干眼症患者临床症状，延长泪膜破裂时间，增加泪液分泌，改善泪膜功能及生活质量，其疗效优于透明质酸钠滴眼液。
