Egloff Chales, Picone Olivier, Vauloup-Fellous Christelle, Roques Pierre
Service de gynécologie-obstétrique, Hôpital Louis Mourier, AP-HP, Université de Paris, IAME Inserm U1137, Paris, France, IDMIT, CEA, Université Paris-Saclay, IMVA Inserm U1184, Fontenay-aux-Roses, France.
Service de gynécologie-obstétrique, Hôpital Louis Mourier, AP-HP, Université de Paris, IAME Inserm U1137, Paris, France.
Virologie (Montrouge). 2020 Jun 1;24(3):142-146. doi: 10.1684/vir.2020.0838.
The emerging coronavirus called SARS-CoV-2 has spread rapidly around the world. Responsible for severe pneumonitis (Covid-19), there are also doubts concerning a possible mother-to-fetal transmission of this virus. Current data are patchy and obtained from small groups of patients. They tend to support the idea that the mother-to-fetal transmission of SARS-CoV-2 is very rare, but the period between infection and childbirth was often very short and may not allow sufficient replication to consider transplacental passage. Here, we reviewed the existing virological data and those remaining to explore. Thus, the natural history of SARS-CoV-2 infection in pregnant women and the risk of transmission in utero is not yet fully understood and defined. Four months from the emergence of this virus, it is therefore reasonable to wait for the results of specific studies on larger cohorts which, to be conclusive, must meet the best scientific criteria.
这种名为严重急性呼吸综合征冠状病毒2（SARS-CoV-2）的新型冠状病毒已在全球迅速传播。它会引发严重肺炎（新冠肺炎），人们也怀疑这种病毒是否存在母婴传播的可能性。目前的数据不完整，且来自少数患者群体。这些数据倾向于支持这样一种观点，即SARS-CoV-2的母婴传播非常罕见，但感染到分娩之间的时间往往很短，可能不足以让病毒进行充分复制以实现经胎盘传播。在此，我们回顾了现有的病毒学数据以及有待探索的数据。因此，孕妇感染SARS-CoV-2的自然病程以及子宫内传播的风险尚未得到充分了解和明确界定。自这种病毒出现四个月以来，等待对更大队列进行的特定研究结果是合理的，而这些研究要具有决定性，就必须符合最佳科学标准。
