Peyronnet V, Sibiude J, Huissoud C, Lescure F-X, Lucet J-C, Mandelbrot L, Nisand I, Belaish-Allart J, Vayssière C, Yazpandanah Y, Luton D, Picone O
Service de gynécologie-obstétrique, hôpital Louis-Mourier, Assistance publique-Hôpitaux de Paris, 92700 Colombes, France.
Service de gynécologie-obstétrique, hôpital Louis-Mourier, Assistance publique-Hôpitaux de Paris, 92700 Colombes, France; Inserm IAME-U1137, 75000 Paris, France; Groupe de recherche sur les infections pendant la grossesse (GRIG), 75000 Paris, France; CNGOF, 91, boulevard de Sébastopol, 75002 Paris, France.
Gynecol Obstet Fertil Senol. 2020 Dec;48(12):858-870. doi: 10.1016/j.gofs.2020.10.001. Epub 2020 Oct 5.
The coronavirus SARS-CoV-2 identified late 2019 in China had spread across all continents. In the majority of cases, patients have mild symptoms (fever, cough, myalgia, headache, some digestive disorders) or are asymptomatic, however it can cause serious lung diseases and lead to death. On September 2020, over 28 million people have been infected with over 920,000 deaths.
In view of the evolution of the epidemic the French National College of Obstetricians and Gynecologists has decided to update the recommendations previously issued. To do this, the same group of experts was called upon to carry out a review of the literature and take into account the opinions of the General Directorate of Health (DGS), the "Haute Autorité de Santé" (HAS) and the "Haut Conseil de santé Publique" (HCSP).
The data on consequences during pregnancy have accumulated. The symptoms in pregnant women appear to be similar to those of the general population, but an increased risk of respiratory distress exists in pregnant women especially in the third trimester. A case of intrauterine maternal-fetal transmission has been clearly identified. Induced prematurity and cases of respiratory distress in newborns of infected mothers have been described.
In light of the new data, we propose updated recommendations. These proposals may continue to evolve in view of the pandemic and of advances in studies in pregnant women.
2019年末在中国发现的新型冠状病毒SARS-CoV-2已蔓延至各大洲。在大多数情况下，患者症状较轻（发热、咳嗽、肌痛、头痛、一些消化系统紊乱）或无症状，然而它可导致严重的肺部疾病并致人死亡。截至2020年9月，已有超过2800万人感染，死亡人数超过92万。
鉴于疫情的发展，法国国家妇产科医师学会决定更新此前发布的建议。为此，同一组专家被要求对文献进行综述，并考虑法国卫生部（DGS）、法国最高卫生管理局（HAS）和法国公共卫生高级委员会（HCSP）的意见。
关于孕期后果的数据不断积累。孕妇的症状似乎与普通人群相似，但孕妇尤其是孕晚期孕妇出现呼吸窘迫的风险增加。已明确确认了一例宫内母婴传播病例。已报道了感染母亲的新生儿出现早产和呼吸窘迫病例。
鉴于新的数据，我们提出更新后的建议。鉴于疫情以及孕妇研究的进展，这些建议可能会继续演变。
