J Cardiovasc Nurs. 2022;37(1):58-63. doi: 10.1097/JCN.0000000000000725.
African Americans are more likely to die from cardiovascular disease (CVD) than all other populations in the United States. Although technological advances have supported rapid growth in applying genetics/genomics to address CVD, most research has been conducted among European Americans. The lack of African American representation in genomic samples has limited progress in equitably applying precision medicine tools, which will widen CVD disparities if not remedied.
This report summarizes the genetic/genomic advances that inform precision health and the implications for cardiovascular disparities in African American adults. We provide nurse scientists recommendations for becoming leaders in developing precision health tools that promote population health equity.
Genomics will continue to drive advances in CVD prevention and management, and equitable progress is imperative. Nursing should leverage the public's trust and its widespread presence in clinical and community settings to prevent the worsening of CVD disparities among African Americans.
在美国，非裔美国人死于心血管疾病（CVD）的可能性比其他所有人群都高。尽管技术进步支持了将遗传学/基因组学应用于解决 CVD 的快速发展，但大多数研究都是在欧洲裔美国人中进行的。由于缺乏非洲裔美国人在基因组样本中的代表性，精准医疗工具的公平应用进展受到限制，如果不加以纠正，这将扩大 CVD 差异。
本报告总结了精准健康相关的遗传/基因组学进展及其对非裔美国成年人心血管差异的影响。我们为护理科学家提供了制定精准健康工具的建议，以促进人口健康公平。
基因组学将继续推动 CVD 预防和管理的进展，公平的进展至关重要。护理应利用公众的信任及其在临床和社区环境中的广泛存在，防止非裔美国人 CVD 差异的恶化。
