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青光眼患者视觉相关生活质量与视觉功能的关系

The Relationship Between Vision-related Quality of Life and Visual Function in Glaucoma Patients.

作者信息

Hirooka Kazuyuki, Sato Shino, Nitta Eri, Tsujikawa Akitaka

机构信息

Department of Ophthalmology, Faculty of Medicine, Kagawa University, Ikenobe, Miki, Kagawa, Japan.

出版信息

J Glaucoma. 2016 Jun;25(6):505-9. doi: 10.1097/IJG.0000000000000372.

Abstract

PURPOSE

To evaluate the relationship between vision-related quality of life (QOL) as measured by the short-form 11-item Japanese version of the Visual Function Questionnaire (VFQ-J11) and the severity of visual field (VF) defects in patients with glaucoma.

METHODS

The study included 134 glaucoma patients and 30 normal subjects. VF testing using the Humphrey Field Analyzer was performed to obtain both the VF index (VFI) and MD in both eyes of each glaucoma patient. Binocular integrated VF was constructed for each patient by merging corresponding sensitivity values from monocular VFs, and the correlation between visual function and vision-related QOL was then assessed.

RESULTS

A significant relationship was found between QOL and VF in 6 of 7 subscales on the VFQ-J11, and between the composite scores in both the better eye and the worse eye in glaucoma patients. The relationship was stronger in the worse eye than in the better eye. Overall, correlation coefficients of the VFI were higher than those of MD and slightly higher than those of integrated VF in the worse eye.

CONCLUSIONS

The VFI showed a marginally better correlation than MD. Assessment of VFI in the worse eye may provide useful information regarding vision-related QOL in glaucoma patients.

摘要

目的

通过日本版11项视觉功能问卷简表(VFQ-J11)评估青光眼患者的视力相关生活质量(QOL)与视野(VF)缺损严重程度之间的关系。

方法

该研究纳入了134例青光眼患者和30名正常受试者。使用Humphrey视野分析仪进行VF检测,以获取每位青光眼患者双眼的VF指数(VFI)和平均偏差(MD)。通过合并单眼VF的相应敏感度值为每位患者构建双眼综合VF,然后评估视觉功能与视力相关QOL之间的相关性。

结果

在VFQ-J11的7个分量表中的6个以及青光眼患者较好眼和较差眼的综合评分之间,发现QOL与VF之间存在显著关系。较差眼中的这种关系比较好眼中更强。总体而言,在较差眼中,VFI的相关系数高于MD的相关系数,且略高于综合VF的相关系数。

结论

VFI显示出比MD稍好的相关性。评估较差眼的VFI可能为青光眼患者的视力相关QOL提供有用信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fcf/4888932/f7923ae4f558/ijg-25-505-g005.jpg

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