Góes Larissa Daniele Machado, Scrignoli Juliana Alves, Morais Patrícia, Talhari Carolina
Tropical Dermatology Clinic, Fundação de Dermatologia Tropical e Venereologia Alfredo da Matta, Manaus, AM, Brazil.
Rheumatology Service, Fundação Hospital Adriano Jorge, Manaus, AM, Brazil.
An Bras Dermatol. 2020 Sep-Oct;95(5):652-654. doi: 10.1016/j.abd.2019.12.007. Epub 2020 Jun 25.
Leprosy is an infectious disease with chronic evolution, caused by Mycobacterium leprae, an acid-fast bacillus that mainly affects the skin and peripheral nervous tissue. Many of the clinical manifestations of leprosy can mimic connective tissue diseases. The authors present the case of a 49-year-old woman who had been treated for four years for systemic lupus erythematosus in a rheumatological service. Skin biopsy of a plaque on the inguinal region was compatible with borderline lepromatous leprosy associated with a type 1 lepra reaction. The patient is undergoing treatment with multibacillary multidrug therapy, showing clinical improvement.
麻风是一种具有慢性病程的传染病,由麻风分枝杆菌引起,这是一种抗酸杆菌,主要影响皮肤和周围神经组织。麻风的许多临床表现可类似于结缔组织疾病。作者报告了一例49岁女性病例,该患者在风湿病科接受系统性红斑狼疮治疗已四年。腹股沟区斑块的皮肤活检结果符合界线类偏瘤型麻风伴1型麻风反应。该患者正在接受多菌型联合化疗,临床症状有所改善。