SeyedAlinaghi SeyedAhmad, Ghadimi Maryam, Hajiabdolbaghi Mahboubeh, Rasoolinejad Mehrnaz, Abbasian Ladan, Nezhad Malihe Hassan, Manshadi SeyedAli Dehghan, Ghadimi Fatemeh, Ahmadinejad Zahra
Iranian Research Center for HIV/AIDS, Iranian Institute for Reduction of High-Risk Behaviors, Tehran University of Medical Sciences, Tehran, Iran
Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, 600 N Wolfe St, Room 143, Baltimore, MD 21287, USA
Curr HIV Res. 2020;18(5):373-380. doi: 10.2174/1570162X18666200712175535.
COVID-19 has spread globally with remarkable speed, and currently, there is limited data available exploring any aspect of the intersection between HIV and SARSCoV- 2 co-infection.
To estimate the prevalence of clinical symptoms associated with COVID-19 among people living with HIV (PLWH) in Tehran, Iran.
Cross-sectional study.
A total of 200 PLWH were recruited through the positive club via sampling, and completed the symptom-based questionnaire for COVID-19, which was delivered by trained peers.
Of 200 participants, respiratory symptoms, including cough, sputum, and shortness of breath, were the most prevalent among participants, but only one person developed symptoms collectively suggested COVID-19 and sought treatments.
It appears that existing infection with HIV or receiving antiretroviral treatment (ART) might reduce the susceptibility to the infection with SARS-CoV-2 or decrease the severity of the infection acquired. Further research is needed to understand causal mechanisms.
新型冠状病毒肺炎（COVID-19）已在全球迅速传播，目前，关于人类免疫缺陷病毒（HIV）与严重急性呼吸综合征冠状病毒2（SARS-CoV-2）合并感染交叉领域任何方面的可用数据有限。
估计伊朗德黑兰感染HIV的人群（PLWH）中与COVID-19相关的临床症状患病率。
横断面研究。
通过阳性俱乐部采用抽样方法共招募了200名PLWH，并完成了由经过培训的同伴发放的基于症状的COVID-19问卷。
在200名参与者中，呼吸道症状，包括咳嗽、咳痰和呼吸急促，在参与者中最为普遍，但只有一人出现了共同提示COVID-19的症状并寻求治疗。
似乎现有的HIV感染或接受抗逆转录病毒治疗（ART）可能会降低感染SARS-CoV-2的易感性或降低获得性感染的严重程度。需要进一步研究以了解因果机制。
