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了解针对新型冠状病毒(COVID-19)的免疫反应和治疗挑战。

Gaining insights on immune responses to the novel coronavirus, COVID-19 and therapeutic challenges.

机构信息

Student Research Committee, Department of Immunology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Department of Immunology, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Department of Immunology, Faculty of Medicine, Tarbiat Modares University, Tehran, Iran; Research Center for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Life Sci. 2020 Sep 15;257:118058. doi: 10.1016/j.lfs.2020.118058. Epub 2020 Jul 9.

DOI:10.1016/j.lfs.2020.118058
PMID:32653518
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7347333/
Abstract

SARS-CoV-2 is a new member of coronaviruses that its sudden spreading put the health care system of most countries in a tremendous shock. For controlling of the new infection, COVID-19, many efforts have been done and are ongoing to defeat this virus in the combat field. In this review, we focused on how the immune system behaves toward the virus and the relative possible consequences during their interactions. Then the therapeutic steps and potential vaccine candidates have been described in a hope to provide a better prospective of effective treatment and preventive strategies to the novel SARS-CoV in near future.

摘要

SARS-CoV-2 是冠状病毒的一个新成员,其突然传播使大多数国家的医疗保健系统受到巨大冲击。为了控制这种新的感染,即 COVID-19,已经并正在进行许多努力来在对抗该病毒的战斗中取得胜利。在这篇综述中,我们重点研究了免疫系统对病毒的反应以及它们相互作用时可能产生的相关后果。然后,我们描述了治疗步骤和潜在的疫苗候选物,希望为新型 SARS-CoV 提供更有效的治疗和预防策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d825/7347333/bec9cc5e871f/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d825/7347333/b5db56892b1b/ga1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d825/7347333/bec9cc5e871f/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d825/7347333/b5db56892b1b/ga1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d825/7347333/bec9cc5e871f/gr1_lrg.jpg

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