Cook D J, Bensen W G, Shore A, Csordas J E
Rheumatic Disease Unit, St. Joseph's Hospital, Toronto, ON, Canada.
J Rheumatol. 1988 Dec;15(12):1865-7.
Type I pauciarticular juvenile rheumatoid arthritis (PA-JRA) is characterized by a female predominance, chronic iridocyclitis and a positive antinuclear antibody (ANA) test. In contrast, patients with type II PA-JRA are usually male, have a negative ANA test, but are HLA-B27 positive. We report a patient with longstanding iridocyclitis who presented at age 20 with oligoarthritis, whom we believe has Type I PA-JRA. Slit lamp examination should be considered in patients with oligoarthritis; the detection of asymptomatic chronic iridocyclitis may aid in the diagnosis. Untreated, this condition may cause irreversible ocular damage.
I型少关节型幼年类风湿性关节炎(PA-JRA)的特点是女性居多、慢性虹膜睫状体炎和抗核抗体(ANA)检测呈阳性。相比之下,II型PA-JRA患者通常为男性,ANA检测呈阴性,但HLA-B27呈阳性。我们报告一例患有长期虹膜睫状体炎的患者,该患者20岁时出现少关节炎,我们认为其患有I型PA-JRA。少关节炎患者应考虑进行裂隙灯检查;无症状慢性虹膜睫状体炎的检测可能有助于诊断。若不治疗,这种情况可能会导致不可逆的眼部损伤。