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传染病中的振荡与混沌:丹麦哥本哈根六种儿童疾病的非线性动力学研究

Oscillations and chaos in epidemics: a nonlinear dynamic study of six childhood diseases in Copenhagen, Denmark.

作者信息

Olsen L F, Truty G L, Schaffer W M

机构信息

Department of Ecology & Evolutionary Biology, University of Arizona, Tucson 85721.

出版信息

Theor Popul Biol. 1988 Jun;33(3):344-70. doi: 10.1016/0040-5809(88)90019-6.

Abstract

Using traditional spectral analysis and recently developed non-linear methods, we analyze the incidence of six childhood diseases in Copenhagen, Denmark. In three cases, measles, mumps, rubella, the dynamics suggest low dimensional chaos. Outbreaks of chicken pox, on the other hand, conform to an annual cycle with noise superimposed. The remaining diseases, pertussis and scarlet fever, remain problematic. The real epidemics are compared with the output of a Monte Carlo analog of the SEIR model for childhood infections. For measles, mumps, rubella, and chicken pox, we find substantial agreement between the model simulations and the data.

摘要

我们运用传统频谱分析方法以及最近开发的非线性方法,对丹麦哥本哈根六种儿童疾病的发病率进行了分析。在麻疹、腮腺炎、风疹这三种疾病的案例中,其动态变化显示出低维混沌特征。另一方面,水痘的爆发呈现出叠加噪声的年度周期规律。其余疾病,百日咳和猩红热,情况仍不明确。我们将实际疫情与儿童感染的SEIR模型的蒙特卡罗模拟输出结果进行了比较。对于麻疹、腮腺炎、风疹和水痘,我们发现模型模拟结果与数据之间存在显著的一致性。

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