Department of Echocardiography, the Affiliated Changzhou No.2 People's Hospital with Nanjing Medical University, Changzhou, 213003, China.
Department of Interventional Radiology, the First Affiliated Hospital of Soochow University, Suzhou, 215006, China.
BMC Cardiovasc Disord. 2020 Jul 13;20(1):335. doi: 10.1186/s12872-020-01610-1.
To detect the right atrial (RA) functions in hypertrophic cardiomyopathy (HCM) patients by using volume-derived values and two-dimensional strain.
Thirty-two HCM patients and 34 age and gender matched normal controls were enrolled for this study. RA volume-derived values were measured by using 2D ultrasonic images. RA strain (S-reservoir, S-conduit, S-booster pump) and strain rate (SR-reservoir, SR-conduit, SR-booster pump), representing the reservoir, conduit and booster pump functions, respectively, were measured by EchoPAC.
Total RA emptying fraction (RAEF) and RA expansion index in HCM patients were significantly lower than normal controls (p < 0.05). The values of S-reservoir, S-conduit, Sr-reservoir and Sr-conduit in HCM patients were significantly lower than normal controls (p < 0.001). Although there were no significant differences in S-booster pump and Sr-booster pump between HCM patients and normal controls, the absolute values in HCM patients were lower than normal controls.
In this study, we concluded that RA dysfunctions, including the reservoir and conduit functions were impaired in HCM patients.
通过容积参数和二维应变来检测肥厚型心肌病（HCM）患者的右心房（RA）功能。
本研究纳入了 32 例 HCM 患者和 34 名年龄和性别匹配的正常对照者。通过二维超声图像测量 RA 容积参数。应用 EchoPAC 测量 RA 应变（S-储备、S-管道、S-助推泵）和应变率（SR-储备、SR-管道、SR-助推泵），分别代表储备、管道和助推泵功能。
HCM 患者的总 RA 排空分数（RAEF）和 RA 扩张指数明显低于正常对照组（p<0.05）。HCM 患者的 S-储备、S-管道、Sr-储备和 Sr-管道值明显低于正常对照组（p<0.001）。尽管 HCM 患者的 S-助推泵和 Sr-助推泵与正常对照组之间没有显著差异，但 HCM 患者的绝对值较低。
在这项研究中，我们得出结论，HCM 患者的 RA 功能障碍，包括储备和管道功能受损。
