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基于智能手机的精神科患者和学生对照的生态瞬时评估(EMA):一项真实世界的可行性研究。

Smartphone-based ecological momentary assessment (EMA) in psychiatric patients and student controls: A real-world feasibility study.

机构信息

Instituto de Investigación Sanitaria Fundación Jiménez Díaz, Madrid, Spain; Department of Psychiatry, Hospital Universitario Rey Juan Carlos, Móstoles, Madrid.

Department of Psychiatry, Hospital Universitario Rey Juan Carlos, Móstoles, Madrid.

出版信息

J Affect Disord. 2020 Sep 1;274:733-741. doi: 10.1016/j.jad.2020.05.067. Epub 2020 May 26.

Abstract

BACKGROUND

Smartphone-based ecological momentary assessment (EMA) is a promising methodology for mental health research. The objective of this study is to determine the feasibility of smartphone-based active and passive EMA in psychiatric outpatients and student controls.

METHODS

Two smartphone applications -MEmind and eB- were developed for behavioral active and passive monitoring. The applications were tested in psychiatric patients with a history of suicidal thoughts and/or behaviors (STB), psychiatric patients without a history of STB, and student controls. Main outcome was feasibility, measured as response to recruitment, retention, and EMA compliance. Secondary outcomes were patterns of smartphone usage.

RESULTS

Response rate was 87.3% in patients with a history of STB, 85.1% in patients without a history of STB, and 75.0% in student controls. 457 participants installed the MEmind app (120 patients with a history of STB and 337 controls) and 1,708 installed the eB app (139 patients with a history of STB, 1,224 patients with no history of STB and 346 controls). For the MEmind app, participants were followed-up for a median of 49.5, resulting in 22,622 person-days. For the eB application, participants were followed-up for a median of 48.9 days, resulting in 83,521 person-days. EMA compliance rate was 65.00% in suicidal patients and 75.21% in student controls. At the end of the follow-up, over 60% of participants remained in the study.

LIMITATIONS

Cases and controls were not matched by age and sex. Cases were patients who were receiving adequate psychopharmacological treatment and attending their appointments, which may result in an overstatement of clinical compliance.

CONCLUSIONS

Smartphone-based active and passive monitoring are feasible methods in psychiatric patients in real-world settings. The development of applications with friendly interfaces and directly useful features can help increase engagement without using incentives. The MEmind and eB applications are promising clinical tools that could contribute to the management of mental disorders. In the near future, these applications could serve as risk monitoring devices in the clinical practice.

摘要

背景

基于智能手机的生态瞬时评估(EMA)是精神健康研究中很有前景的方法。本研究旨在确定基于智能手机的主动和被动 EMA 在精神科门诊患者和学生对照中的可行性。

方法

开发了两种智能手机应用程序-MEmind 和 eB-用于行为主动和被动监测。在有自杀意念和/或行为(STB)病史的精神科患者、无 STB 病史的精神科患者和学生对照中测试了这些应用程序。主要结果是可行性,以对招募、保留和 EMA 依从性的反应来衡量。次要结果是智能手机使用模式。

结果

有 STB 病史的患者的回应率为 87.3%,无 STB 病史的患者为 85.1%,学生对照为 75.0%。457 名参与者安装了 MEmind 应用程序(120 名有 STB 病史的患者和 337 名对照),1708 名参与者安装了 eB 应用程序(139 名有 STB 病史的患者、1224 名无 STB 病史的患者和 346 名对照)。对于 MEmind 应用程序,参与者的中位随访时间为 49.5 天,共 22622 人日。对于 eB 应用程序,参与者的中位随访时间为 48.9 天,共 83521 人日。自杀患者的 EMA 依从率为 65.00%,学生对照为 75.21%。随访结束时,超过 60%的参与者仍在研究中。

局限性

病例和对照未按年龄和性别匹配。病例是正在接受充分精神药理学治疗并按时就诊的患者,这可能导致临床依从性的夸大。

结论

基于智能手机的主动和被动监测是真实环境中精神科患者可行的方法。开发具有友好界面和直接有用功能的应用程序可以帮助提高参与度,而无需使用激励措施。MEmind 和 eB 应用程序是很有前途的临床工具,可有助于管理精神障碍。在不久的将来,这些应用程序可以作为临床实践中的风险监测设备。

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