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睡眠障碍作为想死意愿的临床标志物:为期三个月观察的智能手机监测研究。

Disturbed sleep as a clinical marker of wish to die: A smartphone monitoring study over three months of observation.

机构信息

Instituto de Investigación Sanitaria Fundación Jiménez Díaz, Madrid, Spain.

Department of Signal Theory, Universidad Carlos III de Madrid, Leganés, Spain; Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.

出版信息

J Affect Disord. 2021 May 1;286:330-337. doi: 10.1016/j.jad.2021.02.059. Epub 2021 Mar 5.

Abstract

BACKGROUND

Smartphone monitoring could contribute to the elucidation of the correlates of suicidal thoughts and behaviors (STB). In this study, we employ smartphone monitoring and machine learning techniques to explore the association of wish to die (passive suicidal ideation) with disturbed sleep, altered appetite and negative feelings.

METHODS

This is a prospective cohort study carried out among adult psychiatric outpatients with a history of STB. A daily questionnaire was administered through the MEmind smartphone application. Participants were followed-up for a median of 89.8 days, resulting in 9,878 person-days. Data analysis employed a machine learning technique called Indian Buffet Process.

RESULTS

165 patients were recruited, 139 had the MEmind mobile application installed on their smartphone, and 110 answered questions regularly enough to be included in the final analysis. We found that the combination of wish to die and sleep problems was one of the most relevant latent features found across the sample, showing that these variables tend to be present during the same time frame (96 hours).

CONCLUSIONS

Disturbed sleep emerges as a potential clinical marker for passive suicidal ideation. Our findings stress the importance of evaluating sleep as part of the screening for suicidal behavior. Compared to previous smartphone monitoring studies on suicidal behavior, this study includes a long follow-up period and a large sample.

摘要

背景

智能手机监测有助于阐明自杀意念和行为(STB)的相关因素。在这项研究中,我们采用智能手机监测和机器学习技术来探索想死的愿望(被动自杀意念)与睡眠障碍、食欲改变和负面情绪之间的关联。

方法

这是一项前瞻性队列研究,在有 STB 病史的成年精神科门诊患者中进行。通过 MEmind 智能手机应用程序每天进行问卷调查。参与者的中位随访时间为 89.8 天,共 9878 人天。数据分析采用了一种称为印度自助餐过程的机器学习技术。

结果

共招募了 165 名患者,其中 139 名患者在智能手机上安装了 MEmind 移动应用程序,110 名患者定期回答问题,足以纳入最终分析。我们发现,想死的愿望和睡眠问题的组合是整个样本中发现的最相关的潜在特征之一,这表明这些变量往往在同一时间段(96 小时)内出现。

结论

睡眠障碍是被动自杀意念的一个潜在临床标志物。我们的研究结果强调了评估睡眠作为自杀行为筛查一部分的重要性。与之前关于自杀行为的智能手机监测研究相比,这项研究包括了较长的随访期和较大的样本量。

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Digital phenotyping of suicidal thoughts.自杀意念的数字化表型。
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