短期静脉注射胺碘酮治疗阵发性心房颤动老年患者发生尖端扭转型室性心动过速
TORSADES DE POINTES IN ELDERLY PATIENT WITH PAROXYSMAL ATRIAL FIBRILLATION TREATED BY SHORT-TERM PARENTERAL AMIODARONE THERAPY.
作者信息
Lakušić Nenad, Slivnjak Valentina, Ciglenečki Nedeljko, Cerovec Duško
机构信息
1Department of Cardiology, Krapinske Toplice Hospital for Medical Rehabilitation, Faculty of Medicine and Faculty of Dental Medicine and Health, Josip Juraj Strossmayer University of Osijek, Krapinske Toplice, Croatia; 2Department of Internal Medicine, Krapinske Toplice Hospital for Medical Rehabilitation, Krapinske Toplice, Croatia; 3Intensive Care Unit, Krapinske Toplice Hospital for Medical Rehabilitation, Krapinske Toplice, Croatia.
出版信息
Acta Clin Croat. 2019 Dec;58(4):751-756. doi: 10.20471/acc.2019.58.04.23.
One of the drugs that are widely used in the treatment of atrial fibrillation is amiodarone. Despite considerable prolongation of the corrected QT interval and a substantial degree of bradycardia, amiodarone exhibits a remarkably low frequency of pro-arrhythmic events and <1.0% incidence of torsades de pointes, mostly after long-term usage. We present a case of an 80-year-old female with paroxysmal atrial fibrillation accompanied by acute heart failure treated by short-term parenteral amiodarone therapy and development of torsades de pointes.
胺碘酮是广泛用于治疗心房颤动的药物之一。尽管校正QT间期显著延长且有相当程度的心动过缓，但胺碘酮致心律失常事件的发生率极低，尖端扭转型室速的发生率<1.0%，且大多发生在长期用药后。我们报告一例80岁女性阵发性心房颤动伴急性心力衰竭患者，经短期静脉应用胺碘酮治疗后发生尖端扭转型室速。
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