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瓣膜上的痤疮:两例痤疮丙酸杆菌性心内膜炎的有趣病例。

Acne on the Valve: Two Intriguing Cases of Cutibacterium Acnes Endocarditis.

作者信息

Lodhi Samra Haroon, Abbasi Ayesha, Ahmed Taha, Chan Albert

机构信息

Internal Medicine, King Edward Medical University, Lahore, PAK.

Internal Medicine, Mayo Hospital, Lahore, PAK.

出版信息

Cureus. 2020 Jun 9;12(6):e8532. doi: 10.7759/cureus.8532.

DOI:10.7759/cureus.8532
PMID:32665879
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7352884/
Abstract

Cutibacterium acnes is a skin commensal which is most often regarded as a contaminant when detected on blood cultures. In rare instances, it may be the causative pathogen in severe systemic illnesses. Subacute endocarditis, especially of prosthetic valves and devices, is an important grave pathology caused by Cutibacterium acnes. Herein we report two cases of prosthetic valve endocarditis with varied presentations as valve dehiscence with a "rocking" prosthetic valve apparatus in one encounter and as a septic embolic stroke in the second encounter. Although a rare cause of endocarditis, it becomes an especially important entity in patients with prosthetic devices and should be high in the list of differentials.

摘要

痤疮丙酸杆菌是一种皮肤共生菌,在血培养中检测到时通常被视为污染物。在极少数情况下,它可能是严重全身性疾病的致病病原体。亚急性心内膜炎,尤其是人工瓣膜和器械相关的心内膜炎,是由痤疮丙酸杆菌引起的一种重要的严重病理学情况。在此我们报告两例人工瓣膜心内膜炎病例,表现各异,一例表现为人工瓣膜装置“摇摆”导致瓣膜裂开,另一例表现为脓毒性栓塞性中风。尽管它是心内膜炎的罕见病因,但在有植入器械的患者中它成为一个特别重要的疾病,在鉴别诊断清单中应列为重点考虑对象。

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本文引用的文献

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Near-complete aortic mechanical valve dehiscence due to endocarditis reinfection.因感染性心内膜炎再次感染导致的近乎完全性主动脉机械瓣膜裂开。
Echocardiography. 2018 Jun;35(6):872-875. doi: 10.1111/echo.14008. Epub 2018 May 3.
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Propionibacterium acnes endocarditis: a case series.痤疮丙酸杆菌心内膜炎:病例系列。
Clin Microbiol Infect. 2017 Jun;23(6):396-399. doi: 10.1016/j.cmi.2016.12.026. Epub 2017 Jan 3.
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2015 ESC Guidelines on the management of infective endocarditis: a big step forward for an old disease.2015年欧洲心脏病学会感染性心内膜炎管理指南:一种古老疾病向前迈出的一大步。
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Impact of Healthcare-Associated Infections Connected to Medical Devices-An Update.与医疗设备相关的医疗保健相关感染的影响——最新情况
Microorganisms. 2021 Nov 11;9(11):2332. doi: 10.3390/microorganisms9112332.
5
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BMJ Case Rep. 2021 Jul 29;14(7):e243878. doi: 10.1136/bcr-2021-243878.
Heart. 2016 Jul 1;102(13):992-4. doi: 10.1136/heartjnl-2015-308791. Epub 2016 May 11.
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Prosthetic aortic valve dehiscence: a "rocking" catastrophe.人工主动脉瓣裂开:一场“摇摆”的灾难。
J Echocardiogr. 2016 Dec;14(4):171-172. doi: 10.1007/s12574-016-0294-4. Epub 2016 May 12.
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Prosthetic valve endocarditis due to Propionibacterium acnes.痤疮丙酸杆菌所致人工瓣膜心内膜炎
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