Dadi Nitin Chandra Teja, Radochová Barbora, Vargová Jarmila, Bujdáková Helena
Department of Microbiology and Virology, Faculty of Natural Sciences, Comenius University in Bratislava, 84215 Bratislava, Slovakia.
Microorganisms. 2021 Nov 11;9(11):2332. doi: 10.3390/microorganisms9112332.
Healthcare-associated infections (HAIs) are caused by nosocomial pathogens. HAIs have an immense impact not only on developing countries but also on highly developed parts of world. They are predominantly device-associated infections that are caused by the planktonic form of microorganisms as well as those organized in biofilms. This review elucidates the impact of HAIs, focusing on device-associated infections such as central line-associated bloodstream infection including catheter infection, catheter-associated urinary tract infection, ventilator-associated pneumonia, and surgical site infections. The most relevant microorganisms are mentioned in terms of their frequency of infection on medical devices. Standard care bundles, conventional therapy, and novel approaches against device-associated infections are briefly mentioned as well. This review concisely summarizes relevant and up-to-date information on HAIs and HAI-associated microorganisms and also provides a description of several useful approaches for tackling HAIs.
医疗保健相关感染(HAIs)由医院病原体引起。HAIs不仅对发展中国家,而且对世界高度发达地区都有巨大影响。它们主要是与器械相关的感染,由浮游形式的微生物以及形成生物膜的微生物引起。本综述阐明了HAIs的影响,重点关注与器械相关的感染,如中心静脉导管相关血流感染(包括导管感染)、导管相关尿路感染、呼吸机相关性肺炎和手术部位感染。根据它们在医疗器械上的感染频率提及了最相关的微生物。还简要提到了针对与器械相关感染的标准护理集束、传统疗法和新方法。本综述简明扼要地总结了关于HAIs和HAI相关微生物的相关最新信息,并描述了几种应对HAIs的有用方法。