Shikama Nobuaki, Takiguchi Yasuo, Takeda Masahiko, Mori Naoto, Ishio Naoki
Department of Internal Medicine, Chiba Aoba Municipal Hospital, 1273-2 Aoba-cho, Chuo-ku, Chiba City, Chiba, Japan.
Eur Heart J Case Rep. 2024 Jul 2;8(7):ytae313. doi: 10.1093/ehjcr/ytae313. eCollection 2024 Jul.
While is well known for its potential to cause acne vulgaris, postsurgical infections, and other human infections, few reports have described infections. Thus, the clinical characteristics of as an infectious disease are not well understood. Herein, we describe the characteristics of a case of prosthetic valve infective endocarditis caused by .
An 81-year-old man was admitted to our hospital with fever, general fatigue, and appetite loss. His past medical history included aortic valve replacement surgery and coronary artery bypass grafting for aortic valve stenosis and angina pectoris. Physical examination on admission revealed a body temperature of 39.0°C, blood pressure of 97/68 mmHg, and pulse rate of 101 b.p.m. Transthoracic echocardiography showed no prosthetic valve destruction or malfunction or obvious vegetation adhesion to the prosthetic or other valves. Bacteria initially identified as were detected in two sets of anaerobic blood culture bottles collected upon admission. However, as the samples required 111 and 118 h to become blood culture-positive, the possibility of contaminating bacteria was high. Transoesophageal echocardiography revealed vegetation in the artificial valve. Repeated blood culture revealed the same bacteria; thus, contamination was ruled out, and the diagnosis of infective endocarditis was confirmed. Finally, 16S ribosomal RNA gene sequencing identified the detected bacteria as rather than .
Including this case, only two cases of prosthetic valve infective endocarditis caused by have been reported, the characteristics of which are still poorly understood.
虽然[具体细菌名称]因其引发寻常痤疮、术后感染及其他人类感染的可能性而广为人知，但关于[具体细菌名称]感染的报道却很少。因此，作为一种传染病，[具体细菌名称]的临床特征尚未得到充分了解。在此，我们描述一例由[具体细菌名称]引起的人工瓣膜感染性心内膜炎病例的特征。
一名81岁男性因发热、全身乏力和食欲减退入院。他既往有主动脉瓣置换手术及因主动脉瓣狭窄和心绞痛进行冠状动脉搭桥手术史。入院时体格检查显示体温39.0°C，血压97/68 mmHg，脉搏率101次/分钟。经胸超声心动图未显示人工瓣膜破坏或功能障碍，也未显示人工瓣膜或其他瓣膜有明显的赘生物附着。入院时采集的两组厌氧血培养瓶中检测到最初被鉴定为[具体细菌名称]的细菌。然而，由于样本分别需要111小时和118小时才出现血培养阳性，污染细菌的可能性很高。经食管超声心动图显示人工瓣膜有赘生物。重复血培养显示为同一细菌；因此排除了污染，确诊为感染性心内膜炎。最后，16S核糖体RNA基因测序确定检测到的细菌为[具体细菌名称]而非[另一种细菌名称]。
包括本病例在内，仅报道了两例由[具体细菌名称]引起的人工瓣膜感染性心内膜炎病例，其特征仍知之甚少。
